Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | STS | P08842 | 2/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16130140 | 0.88 | LTA4H (0.52) | KDM4EPKMSTSPTPN2PTPN1 | |
| SCHEMBL15539667 | 0.88 | FPR2 (0.61) | KDM4EPKMPTPN2PTPN1PTPN6 | |
| SCHEMBL12258638 | 0.88 | KDM4E (0.58) | KDM4EPKMPTPN2PTPN1PTPN6 | |
| SCHEMBL3087666 | 0.88 | KDM4E (0.70) | KDM4EPKMSTSPTPN2PTPN1 | |
| SCHEMBL3032509 | 0.86 | TGFBR1 (0.56) | KDM4EPKMSTSTGFBR1GPR119 | |
| SCHEMBL6148442 | 0.85 | CYP2D6 (0.64) | KDM4EPKMPTPN2PTPN1PTPN6 | |
| SCHEMBL3980865 | 0.85 | KDM4E (0.53) | KDM4EPKMPTPN2PTPN1PTPN6 | |
| SCHEMBL14255786 | 0.85 | GPR119 (0.57) | KDM4EPKMPTPN2PTPN1PTPN6 | |
| SCHEMBL3979358 | 0.84 | KDM4E (0.57) | KDM4EPKMSTSHTTMEN1 | |
| SCHEMBL20615733 | 0.83 | KDM4E (0.79) | KDM4EPKMSTSALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234427-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH A/S (DK) | 2010-09-16 | — | — | US | disclosed |
| EP-1987001-B1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH AS (DK) | 2010-05-05 | — | — | EP | disclosed |
| EP-1987001-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NeuroSearch A/S (DK) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093603-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | NEUROSEARCH A/S (DK) | 2007-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234427-A1 | 1-PHENETHYLPIPERIDINE DERIVATIVES AND THEIR USE AS OPIOID RECEPTOR LIGANDS | OPRL1, OPRM1, OPRK1 | KDM4E 622/4885PKM 1707/4885STS 4825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.