Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.96 |
| ▸ | GAA | P10253 | 5/20 | 0.96 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.96 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.96 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.96 |
| ▸ | RAB9A | P51151 | 3/20 | 0.96 |
| ▸ | MEN1 | O00255 | 2/20 | 0.96 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.96 |
| ▸ | THRB | P10828 | 2/20 | 0.96 |
| ▸ | RECQL | P46063 | 2/20 | 0.96 |
| ▸ | HTT | P42858 | 2/20 | 0.96 |
| ▸ | MMP14 | P50281 | 1/20 | 0.96 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | APP | P05067 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | SNCA | P37840 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30039228 | 1.00 | MAPT (0.96) | MAPTGAAKDM4EALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL6438776 | 0.98 | MAPT (1.00) | MAPTGAAKDM4EALDH1A1TDP1 | |
| SCHEMBL6652801 | 0.88 | MAPT (0.75) | MAPTGAAKDM4EALDH1A1TDP1 | |
| SCHEMBL1921461 | 0.86 | RAB9A (0.72) | MAPTGAAKDM4EALDH1A1TDP1 | |
| SCHEMBL4607773 | 0.84 | MAPT (0.86) | MAPTGAAKDM4EALDH1A1TDP1 | |
| SCHEMBL27546857 | 0.82 | MAPT (0.73) | MAPTGAAKDM4EALDH1A1TDP1 | |
| SCHEMBL4924540 | 0.81 | MAPT (0.67) | MAPTGAAKDM4EALDH1A1TDP1 | |
| SCHEMBL3977426 | 0.81 | MAPT (0.68) | MAPTGAAKDM4EALDH1A1TDP1 | |
| SCHEMBL4945734 | 0.81 | GAA (0.66) | MAPTGAAKDM4EALDH1A1TDP1 | |
| SCHEMBL5832931 | 0.81 | MAPT (0.66) | MAPTGAAKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1599964-B | Electroactive polymers and devices made therefrom | DOW GLOBAL TECHNOLOGIES INC | 2010-05-12 | — | — | CN | claimed |
| CN-1599964-A | Electroactive polymers and devices made therefrom | DOW CHEMICAL CO (US) | 2005-03-23 | — | — | CN | claimed |
| CN-110870089-B | Organic electroluminescent blue light-emitting device | 三星显示有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-110915013-B | Organic electroluminescent blue light-emitting device | 三星显示有限公司 | 2022-12-02 | — | — | CN | disclosed |
| US-10730842-B2 | Small molecule inhibitors of DYRK1A and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2020-08-04 | — | — | US | disclosed |
| US-10730842-B2 | Small molecule inhibitors of DYRK1A and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2020-08-04 | — | — | US | disclosed |
| CN-110915013-A | Organic electroluminescent blue light-emitting device | 赛诺拉有限公司 | 2020-03-24 | — | — | CN | disclosed |
| CN-110870089-A | Organic electroluminescent blue light-emitting device | 赛诺拉有限公司 | 2020-03-06 | — | — | CN | disclosed |
| CN-107011268-B | The 1,3,6,8- tetra- of bipolarity D- π-A configuration replaces pyrenyl material and preparation method and application | 中国矿业大学 | 2019-07-23 | — | — | CN | disclosed |
| US-20190055212-A1 | HISTONE DEMETHYLASE INHIBITORS | GWALTNEY STEPHEN (US) | 2019-02-21 | — | — | US | disclosed |
| WO-2017143011-A1 | HISTONE DEMETHYLASE INHIBITORS | Chrysalis, Inc. (US) | 2017-08-24 | — | — | WO | disclosed |
| WO-2002028839-A1 | BENZIMIDAZOLE AND INDOLE DERIVATIVES AS CRF RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |
| US-4296114-A | 3,4-Dihydro-3-oxopyrido[2,3-b]-pyrazines, compositions and use thereof | FISONS LIMITED (GB) | 1981-10-20 | — | — | US | disclosed |
| US-4224445-A | ANTIINFLAMMATORY, ANALGESIC, ANTIRHEUMATIC | HOFFMANN-LA ROCHE INC. (US) | 1980-09-23 | — | — | US | disclosed |
| EP-0008864-A1 | Pyridopyrazine and quinoxaline derivatives, processes for their preparation, and pharmaceutical compositions containing them | FISONS plc (GB) | 1980-03-19 | — | — | EP | disclosed |
| US-4177193-A | ALKOXYCARBONYL, ALKYLAMINOSULFONYL-SUBSTITUTED THIOPHENE INTERMEDIATES FOR THE 4-HYDROXY-N-SUBSTITUTED-2H-THIENO(2,3-E)-1,2-THIAZINE-3-CARBOXAMIDE-1,1 -DIOXIDES; ANTIINFLAMMATORY, ANALGESIC | HOFFMAN-LA ROCHE INC. (US) | 1979-12-04 | — | — | US | disclosed |
| US-4134898-A | ANTIINFLAMMATORY, ANALGESIC, ANTIRHEUMATIC | HOFFMANN-LA ROCHE INC. (US) | 1979-01-16 | — | — | US | disclosed |
| US-4076709-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIRHEUMATIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1978-02-28 | — | — | US | disclosed |
| US-4009994-A | Process and product of optical brightening with quaternized benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1977-03-01 | — | — | US | disclosed |
| US-3940417-A | Quaternised benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1976-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10730842-B2 | Small molecule inhibitors of DYRK1A and uses thereof | DYRK1A, DYRK2, DYRK1B | MAPT 219/4885GAA 2319/4885KDM4E 1699/4885 |
| US-20190055212-A1 | HISTONE DEMETHYLASE INHIBITORS | KDM1B, KDM6B, KDM5B | MAPT 2989/4885GAA 1000/4885KDM4E 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.