Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27759034 | 0.82 | ACHE (0.63) | ACHEALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL24036424 | 0.81 | ACHE (0.54) | ACHEALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL3978887 | 0.79 | ACHE (0.43) | ACHEALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL2187671 | 0.77 | L3MBTL1 (0.45) | ACHEALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL2187074 | 0.75 | L3MBTL1 (0.44) | ACHEALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL12492471 | 0.74 | L3MBTL1 (0.46) | ACHEALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL22064000 | 0.73 | L3MBTL1 (0.49) | ALDH1A1HPGDKDM4EL3MBTL1GRM2 | |
| SCHEMBL24828550 | 0.73 | L3MBTL1 (0.49) | ACHEALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL27645962 | 0.72 | L3MBTL1 (0.55) | ACHEALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL20541050 | 0.71 | L3MBTL1 (0.44) | ACHEALDH1A1HPGDKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541374-B2 | Malononitrile compounds and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-02 | — | — | US | disclosed |