SCHEMBL3979928

SCHEMBL3979928

CC(C)(C)c1cc(O)ccc1C(c1ccccc1)c1ccc(O)cc1C(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.49
ALDH1A1 P00352 5/20 0.48
CYP2C9 P11712 2/20 0.48
NR1I2 O75469 1/20 0.48
LMNA P02545 1/20 0.48
MIF P14174 1/20 0.48
ALOX15 P16050 1/20 0.48
HTT P42858 1/20 0.48
NFE2L2 Q16236 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TSHR P16473 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
TDP1 Q9NUW8 2/20 0.38
GAA P10253 2/20 0.37
KMT2A Q03164 1/20 0.37
NQO1 P15559 1/20 0.36
ESR2 Q92731 3/20 0.36
ESR1 P03372 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11867420 0.85 TYR (0.65) TYRALDH1A1CYP2C9NR1I2LMNA
SCHEMBL2799339 0.83 TYR (0.46) TYRALDH1A1CYP2C9NR1I2LMNA
SCHEMBL3322503 0.81 CYP2C9 (0.45) TYRALDH1A1CYP2C9NR1I2LMNA
SCHEMBL9176167 0.79 ALOX15 (0.52) TYRALDH1A1CYP2C9NR1I2LMNA
SCHEMBL28296891 0.79 TSHR (0.48) TYRALDH1A1CYP2C9ALOX15HSD17B10
SCHEMBL1238122 0.77 CYP2C9 (0.42) TYRALDH1A1CYP2C9NR1I2LMNA
SCHEMBL29874711 0.77 CYP2C9 (0.42) TYRALDH1A1CYP2C9NR1I2LMNA
SCHEMBL3325197 0.77 TYR (0.53) TYRALDH1A1LMNAALOX15HSD17B10
SCHEMBL51791 0.76 TYR (0.52) TYRALDH1A1CYP2C9NR1I2LMNA
SCHEMBL84243 0.76 TYR (0.67) TYRALDH1A1TDP1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1469026-B1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDING MATERIAL AND OPTICAL PART IDEMITSU KOSAN CO (JP) 2009-05-06 EP disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-20060270823-A1 Suited to a molding material for an optical disc substrate such as a digital audio disc, a digital video disc and an optical memory disc, various lenses such as a lens for an optical pickup, spectacle lenses, contact lenses and a lens sheet, an optical sheet substrate IDEMITSU KOSAN CO., LTD (JP) 2006-11-30 US disclosed
US-7112644-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2006-09-26 US disclosed
EP-1361241-B1 Process for producing raw polycarbonate resin material and producing polycarbonate resin IDEMITSU KOSAN CO (JP) 2005-08-24 EP disclosed
US-20050143553-A1 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD (JP) 2005-06-30 US disclosed
EP-1178068-B1 PROCESSES FOR PRODUCING RAW POLYCARBONATE RESIN MATERIAL AND PRODUCING POLYCARBONATE RESIN IDEMITSU KOSAN CO (JP) 2005-05-18 EP disclosed
EP-1469026-A1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDINGMATERIAL AND OPTICAL PART IDEMITSU KOSAN CO., LTD. (JP) 2004-10-20 EP disclosed
EP-1361241-A1 Process for producing raw polycarbonate resin material and producing polycarbonate resin IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-11-12 EP disclosed
EP-1178068-A1 PROCESSES FOR PRODUCING RAW POLYCARBONATE RESIN MATERIAL AND PRODUCING POLYCARBONATE RESIN IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-02-06 EP disclosed