Psoralen

Psoralen

SCHEMBL3980090

O=c1ccc2cc3ccoc3cc2o1.O=c1ccc2ccc3occc3c2o1

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.77
NFKB1 P19838 2/20 0.77
MAOB P27338 2/20 0.77
CYP3A4 P08684 7/20 0.73
KDM4E B2RXH2 6/20 0.73
HSD17B10 Q99714 5/20 0.73
CYP2A6 P11509 4/20 0.73
ACHE P22303 4/20 0.73
CYP2D6 P10635 3/20 0.73
CYP2C19 P33261 3/20 0.73
CYP2C9 P11712 2/20 0.73
ALDH1A1 P00352 6/20 0.49
MAPT P10636 4/20 0.49
HPGD P15428 3/20 0.48
GAA P10253 2/20 0.48
NPC1 O15118 1/20 0.48
MGAM O43451 1/20 0.48
SI P14410 1/20 0.48
PTPN1 P18031 1/20 0.48
RAB9A P51151 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Angelicin SCHEMBL8726499 0.87 MAOA (1.00) MAOANFKB1MAOBCYP3A4KDM4E
Angelicin SCHEMBL29468230 0.87 MAOA (1.00) MAOANFKB1MAOBCYP3A4KDM4E
Angelicin SCHEMBL376379 0.87 MAOA (1.00) MAOANFKB1MAOBCYP3A4KDM4E
Psoralen SCHEMBL2684633 0.86 MAOA (1.00) MAOANFKB1MAOBCYP3A4KDM4E
Psoralen SCHEMBL29503678 0.86 MAOA (1.00) MAOANFKB1MAOBCYP3A4KDM4E
Psoralen SCHEMBL17835 0.86 MAOA (1.00) MAOANFKB1MAOBCYP3A4KDM4E
Psoralen SCHEMBL8707426 0.84 MAOA (0.96) MAOANFKB1MAOBCYP3A4KDM4E
Psoralen SCHEMBL29165499 0.84 MAOA (0.96) MAOANFKB1MAOBCYP3A4KDM4E
Psoralen SCHEMBL3647286 0.84 MAOA (0.96) MAOANFKB1MAOBCYP3A4KDM4E
Psoralen SCHEMBL27405230 0.84 MAOA (0.96) MAOANFKB1MAOBCYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012105990-A1 BAKUCHIOL COMPOSITIONS FOR TREATMENT OF POST INFLAMMATORY HYPERPIGMENTATION UNIGEN, INC. (US) 2012-08-09 WO disclosed
EP-1881839-A4 COMPOSITIONS OF BAKUCHIOL AND METHODS OF MAKING THE SAME UNIGEN PHARMACEUTICALS INC (US) 2009-05-20 EP disclosed
EP-1881839-A2 COMPOSITIONS OF BAKUCHIOL AND METHODS OF MAKING THE SAME Unigen Pharmaceuticals, Inc. (US) 2008-01-30 EP disclosed
WO-2006122160-A2 COMPOSITIONS OF BAKUCHIOL AND METHODS OF MAKING THE SAME UNIGEN PHARMACEUTICALS, INC. (US) 2006-11-16 WO disclosed