Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 1.00 |
| ▸ | MAOB | P27338 | 2/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Angelicin SCHEMBL29468230 | 1.00 | MAOA (1.00) | MAOAMAOBNFKB1CYP3A4ALDH1A1 | |
| Angelicin SCHEMBL376379 | 1.00 | MAOA (1.00) | MAOAMAOBNFKB1CYP3A4ALDH1A1 | |
| Psoralen SCHEMBL3980090 | 0.87 | MAOA (0.77) | MAOAMAOBNFKB1CYP3A4ALDH1A1 | |
| SCHEMBL31237232 | 0.78 | MAOA (0.63) | MAOAMAOBNFKB1CYP3A4ALDH1A1 | |
| SCHEMBL13784419 | 0.78 | MAOA (0.63) | MAOAMAOBNFKB1CYP3A4ALDH1A1 | |
| SCHEMBL29752613 | 0.77 | MAOA (0.62) | MAOAMAOBNFKB1CYP3A4ALDH1A1 | |
| SCHEMBL623741 | 0.77 | MAOA (0.62) | MAOAMAOBNFKB1CYP3A4ALDH1A1 | |
| Chalcone SCHEMBL22719976 | 0.77 | MAOB (0.59) | MAOAMAOBNFKB1CYP3A4ALDH1A1 | |
| SCHEMBL31238062 | 0.75 | MAOA (0.63) | MAOAMAOBNFKB1CYP3A4ALDH1A1 | |
| SCHEMBL30728734 | 0.75 | MAOA (0.60) | MAOAMAOBNFKB1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5832931-A | Method for improved selectivity in photo-activation and detection of molecular diagnostic agents | PHOTOGEN, INC. (US) | 1998-11-10 | — | — | US | disclosed |
| US-5829448-A | ANTITUMOR | PHOTOGEN, INC. (US) | 1998-11-03 | — | — | US | disclosed |