Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 18/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1730689 | 0.99 | F2R (0.79) | F2R | |
| Trifluoroacetic Acid SCHEMBL1729004 | 0.97 | F2R (0.73) | F2R | |
| Trifluoroacetic Acid SCHEMBL1730610 | 0.97 | F2R (0.73) | F2R | |
| Trifluoroacetic Acid SCHEMBL1729186 | 0.97 | F2R (0.73) | F2R | |
| SCHEMBL14449199 | 0.96 | F2R (0.79) | F2R | |
| SCHEMBL1730350 | 0.95 | F2R (0.76) | F2R | |
| Bromide SCHEMBL5488484 | 0.95 | F2R (0.80) | F2R | |
| Bromide SCHEMBL1730775 | 0.95 | F2R (0.80) | F2R | |
| SCHEMBL1729685 | 0.95 | F2R (0.82) | F2R | |
| Bromide SCHEMBL1732489 | 0.94 | F2R (0.84) | F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658620-B2 | Pharmaceutical composition, use of 2-iminopyrrolidine derivative for production of pharmaceutical composition, and kit for treatment or amelioration of heart diseases | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2014-02-25 | — | — | US | disclosed |
| US-8658620-B2 | Pharmaceutical composition, use of 2-iminopyrrolidine derivative for production of pharmaceutical composition, and kit for treatment or amelioration of heart diseases | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2014-02-25 | — | — | US | disclosed |
| US-20100286087-A1 | PHARMACEUTICAL COMPOSITION, USE OF 2-IMINOPYRROLIDINE DERIVATIVE FOR PRODUCTION OF PHARMACEUTICAL COMPOSITION, AND KIT FOR TREATMENT OR AMELIORATION OF HEART DISEASES | EISAI R&D MANAGEMENT CO, LTD. (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100286087-A1 | PHARMACEUTICAL COMPOSITION, USE OF 2-IMINOPYRROLIDINE DERIVATIVE FOR PRODUCTION OF PHARMACEUTICAL COMPOSITION, AND KIT FOR TREATMENT OR AMELIORATION OF HEART DISEASES | EISAI R&D MANAGEMENT CO, LTD. (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100063048-A1 | Remedy for angiospasm accompanying subarachnoid hemorrhage containing thrombin receptor antagonist as the active ingredient | Eisai R&D Mangement Co., Ltd. (JP) | 2010-03-11 | — | — | US | disclosed |
| US-20100063048-A1 | Remedy for angiospasm accompanying subarachnoid hemorrhage containing thrombin receptor antagonist as the active ingredient | Eisai R&D Mangement Co., Ltd. (JP) | 2010-03-11 | — | — | US | disclosed |
| US-7612066-B2 | Composition containing benzamidine derivative and method for stabilizing benzamidine derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| US-7612066-B2 | Composition containing benzamidine derivative and method for stabilizing benzamidine derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| US-7612066-B2 | Composition containing benzamidine derivative and method for stabilizing benzamidine derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| EP-1721610-B1 | COMPOSITION CONTAINING BENZAMIDINE DERIVATIVE AND METHOD FOR STABILIZING BENZAMIDINE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2009-05-13 | — | — | EP | disclosed |
| EP-1721610-B1 | COMPOSITION CONTAINING BENZAMIDINE DERIVATIVE AND METHOD FOR STABILIZING BENZAMIDINE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2009-05-13 | — | — | EP | disclosed |
| US-20090022729-A1 | METHODS AND COMPOSITIONS FOR TREATING CARDIAC DYSFUNCTIONS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-01-22 | — | — | US | disclosed |
| US-20090022729-A1 | METHODS AND COMPOSITIONS FOR TREATING CARDIAC DYSFUNCTIONS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-01-22 | — | — | US | disclosed |
| US-20080194559-A1 | Remedy for Angiospasm Accompanying Subarachnoid Hemorrhage Containing Thrombin Receptor Antagonist as the Active Ingredient | EISAI R.& D MANAGMENT CO., LTD. (JP) | 2008-08-14 | — | — | US | disclosed |
| US-20080194559-A1 | Remedy for Angiospasm Accompanying Subarachnoid Hemorrhage Containing Thrombin Receptor Antagonist as the Active Ingredient | EISAI R.& D MANAGMENT CO., LTD. (JP) | 2008-08-14 | — | — | US | disclosed |
| US-20070208016-A1 | Composition Containing Benzamidine Derivative and Method For Stabilizing Benzamidine Derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-09-06 | — | — | US | disclosed |
| US-20070208016-A1 | Composition Containing Benzamidine Derivative and Method For Stabilizing Benzamidine Derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-09-06 | — | — | US | disclosed |
| US-20070208016-A1 | Composition Containing Benzamidine Derivative and Method For Stabilizing Benzamidine Derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-09-06 | — | — | US | disclosed |
| EP-1721610-A1 | COMPOSITION CONTAINING BENZAMIDINE DERIVATIVE AND METHOD FOR STABILIZING BENZAMIDINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2006-11-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063048-A1 | Remedy for angiospasm accompanying subarachnoid hemorrhage containing thrombin receptor antagonist as the active ingredient | F2R, F2RL1, PLAT | F2R 1/4885 |
| US-20070208016-A1 | Composition Containing Benzamidine Derivative and Method For Stabilizing Benzamidine Derivative | CMA1, DDC, GBA1 | F2R 4361/4885 |
| US-20090022729-A1 | METHODS AND COMPOSITIONS FOR TREATING CARDIAC DYSFUNCTIONS | TNNI3, MYLK2, FABP3 | F2R 8/4885 |
| US-20100286087-A1 | PHARMACEUTICAL COMPOSITION, USE OF 2-IMINOPYRROLIDINE DERIVATIVE FOR PRODUCTION OF PHARMACEUTICAL COMPOSITION, AND KIT FOR TREATMENT OR AMELIORATION OF HEART DISEASES | KIT, TNNT2, TNNI3 | F2R 1051/4885 |
| US-20080194559-A1 | Remedy for Angiospasm Accompanying Subarachnoid Hemorrhage Containing Thrombin Receptor Antagonist as the Active Ingredient | F2R, F2RL1, PLAT | F2R 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.