SCHEMBL3980256

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3974845	0.98	LMNA (0.49)	LMNATP53MAPK1RAB9AC5AR1
	SCHEMBL4267800	0.96	LMNA (0.48)	LMNATP53MAPK1RAB9AC5AR1
	SCHEMBL4086824	0.89	BCL9 (0.45)	LMNASMN1; SMN2
	SCHEMBL4084588	0.88	CYP1A2 (0.45)	LMNATP53MAPK1RAB9AC5AR1
	SCHEMBL4080746	0.88	SIRT2 (0.41)	LMNARAB9AC5AR1ALDH1A1PRSS1
	SCHEMBL3977087	0.87	PRSS1 (0.54)	LMNATP53RAB9AALDH1A1TYR
	SCHEMBL4980199	0.87	C5AR1 (0.45)	LMNATP53MAPK1RAB9AC5AR1
	SCHEMBL4980619	0.87	CYP1A2 (0.50)	LMNAMAPK1C5AR1ALDH1A1KDM4E
	SCHEMBL4979385	0.86	MAPT (0.40)	LMNAPRSS1SMN1; SMN2KMT2A
	SCHEMBL3975168	0.86	F2 (0.48)	LMNATP53RAB9AALDH1A1TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.