SCHEMBL4084588

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4267800	0.91	LMNA (0.48)	ALDH1A1LMNAC5AR1SMN1; SMN2TP53
	SCHEMBL4980199	0.90	C5AR1 (0.45)	CYP1A2SYKALDH1A1LMNACYP3A4
	SCHEMBL4980619	0.90	CYP1A2 (0.50)	CYP1A2SIRT2ALDH1A1LMNATHRB
	SCHEMBL4086824	0.90	BCL9 (0.45)	SIRT2LMNASMN1; SMN2FABP1MAPT
	SCHEMBL3974845	0.90	LMNA (0.49)	ALDH1A1LMNAC5AR1SMN1; SMN2TP53
	SCHEMBL4080746	0.89	SIRT2 (0.41)	SIRT2ALDH1A1LMNAC5AR1FABP1
	SCHEMBL3980256	0.88	LMNA (0.49)	ALDH1A1LMNAC5AR1SMN1; SMN2TP53
	SCHEMBL3978011	0.88	CYP1A2 (0.50)	CYP1A2SIRT2ALDH1A1CYP3A4CYP2C9
	SCHEMBL14215452	0.87	F10 (0.41)	SIRT2LMNAC5AR1FABP1
	SCHEMBL3984312	0.86	KIF11 (0.46)	SIRT2ALDH1A1LMNAL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.