Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | HRH1 | P35367 | 1/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | NAAA | Q02083 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3976758 | 1.00 | PLK1 (0.61) | PLK1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL3981507 | 1.00 | PLK1 (0.61) | PLK1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL3981757 | 1.00 | PLK1 (0.61) | PLK1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL13382890 | 0.99 | PLK1 (0.63) | PLK1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL24219845 | 0.95 | PLK1 (0.64) | PLK1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL12705231 | 0.90 | PLK1 (0.61) | PLK1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL1041626 | 0.87 | HTR1A (0.62) | PLK1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL1041880 | 0.87 | HTR1A (0.62) | PLK1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL12422565 | 0.86 | PLK1 (0.63) | PLK1HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL3982865 | 0.84 | HTR1A (0.62) | PLK1HTR1AADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009057668-A1 | AMIDE COMPOUND AND PLANT DISEASE CONTROL USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-05-07 | — | — | WO | disclosed |