Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PAM | P19021 | 2/20 | 0.55 |
| ▸ | CES2 | O00748 | 3/20 | 0.54 |
| ▸ | CES1 | P23141 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.52 |
| ▸ | PPARG | P37231 | 6/20 | 0.52 |
| ▸ | PPARD | Q03181 | 6/20 | 0.52 |
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27778361 | 1.00 | DGKA (0.61) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL28126216 | 1.00 | DGKA (0.61) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL27771053 | 1.00 | DGKA (0.61) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL27640216 | 1.00 | DGKA (0.61) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL2734310 | 1.00 | DGKA (0.61) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL329071 | 1.00 | DGKA (0.61) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL740818 | 1.00 | DGKA (0.61) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL8645409 | 1.00 | DGKA (0.61) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL4288902 | 1.00 | DGKA (0.61) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL28057936 | 1.00 | DGKA (0.61) | DGKALMNAPAMCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108866006-A | A kind of preparation method and applications of anti-buprenorphine hybridoma cell strain, antibody | 杭州隆基生物技术有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-108047071-A | A kind of Cathinone artificial semiantigen, artificial antigen and its preparation method and application | 杭州同舟生物技术有限公司 | 2018-05-18 | — | — | CN | claimed |
| CN-110325517-A | Volution compound and its application | 南京明德新药研发有限公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-107001371-B | Oxipurinol class compound and its application | 广东众生睿创生物科技有限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-108866006-A | A kind of preparation method and applications of anti-buprenorphine hybridoma cell strain, antibody | 杭州隆基生物技术有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-108752210-A | A kind of preparation method of germacrone ketobutyric acid | 东南大学成贤学院 | 2018-11-06 | — | — | CN | disclosed |
| CN-108659000-A | Heterocyclic compound and preparation method thereof | 成都海创药业有限公司 | 2018-10-16 | — | — | CN | disclosed |
| CN-108348525-A | The medical usage of oxipurinol class compound | 广东众生药业股份有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-108333349-A | A kind of 4- methyl methcathinone artificial antigen and preparation method and utilization | 浙江东方基因生物制品股份有限公司 | 2018-07-27 | — | — | CN | disclosed |
| CN-108047071-A | A kind of Cathinone artificial semiantigen, artificial antigen and its preparation method and application | 杭州同舟生物技术有限公司 | 2018-05-18 | — | — | CN | disclosed |
| CN-107428705-A | Histone deacetylase inhibitor and preparation method and application thereof | 广东众生药业股份有限公司 | 2017-12-01 | — | — | CN | disclosed |
| WO-2009049476-A1 | PROCESS FOR THE MANUFACTURE OF (+)-BIOTIN | DSM IP ASSETS B.V. (NL) | 2009-04-23 | — | — | WO | disclosed |
| EP-0789577-B1 | SYNTHESIS OF N-SUBSTITUTED OLIGOMERS | CHIRON CORP (US) | 2003-03-12 | — | — | EP | disclosed |
| CN-1314906-A | Salts of paroxetine | SMITHKLINE BEECHAM PLC (GB) | 2001-09-26 | — | — | CN | disclosed |
| US-5877278-A | SOLID PHASE SYNTHESIS USING TWO SUBMONOMERS-AN ACYLATING AGENT, E.G. A HALOACETIC ACID, AND A PRIMARY AMINE; CYCLIZATION TO PRODUCE MIMETICS OF DRUGS; ELIMINATION OF THE NECESSITY OF PROTECTION GROUPS | CHIRON CORPORATION (US) | 1999-03-02 | — | — | US | disclosed |
| EP-0266949-B1 | TETRAHYDROISOQUINOLIN-2-YL DERIVATIVES OF CARBOXYLIC ACIDS AS THROMBOXANE A2 ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |
| US-4812573-A | ARYLSULFONAMIDE SUBSTITUTED TETRAHYDROISOQUINOLINYLALKANOIC ACIDS AS THROMBOXANE A2 ANTAGONISTS | SMITHKLINE & FRENCH LABORATORIES, LTD. (GB) | 1989-03-14 | — | — | US | disclosed |
| EP-0266949-A1 | Tetrahydroisoquinolin-2-yl derivatives of carboxylic acids as thromboxane A2 antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1988-05-11 | — | — | EP | disclosed |
| WO-1988003137-A1 | TETRAHYDROISOQUINOLIN-2-YL DERIVATIVES OF CARBOXYLIC ACIDS AS THROMBOXANE A2 ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1988-05-05 | — | — | WO | disclosed |
| US-4464535-A | Process for the preparation of eburnamonine derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-08-07 | — | — | US | disclosed |