SCHEMBL740818

SCHEMBL740818

CCCCCCCCCCC(=O)OBr

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.61
LMNA P02545 2/20 0.57
PAM P19021 2/20 0.55
CES2 O00748 3/20 0.54
CES1 P23141 3/20 0.54
MAPT P10636 1/20 0.53
MAPK1 P28482 1/20 0.53
GPR84 Q9NQS5 6/20 0.52
PPARG P37231 6/20 0.52
PPARD Q03181 6/20 0.52
PPARA Q07869 6/20 0.52
HDAC11 Q96DB2 5/20 0.52
TSHR P16473 4/20 0.52
ALDH1A1 P00352 2/20 0.52
TLR2 O60603 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
FABP4 P15090 2/20 0.52
PTPN1 P18031 2/20 0.52
SLC22A6 Q4U2R8 1/20 0.52
SLC22A8 Q8TCC7 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27778361 1.00 DGKA (0.61) DGKALMNAPAMCES2CES1
SCHEMBL28126216 1.00 DGKA (0.61) DGKALMNAPAMCES2CES1
SCHEMBL27771053 1.00 DGKA (0.61) DGKALMNAPAMCES2CES1
SCHEMBL27640216 1.00 DGKA (0.61) DGKALMNAPAMCES2CES1
SCHEMBL2734310 1.00 DGKA (0.61) DGKALMNAPAMCES2CES1
SCHEMBL329071 1.00 DGKA (0.61) DGKALMNAPAMCES2CES1
SCHEMBL3980640 1.00 DGKA (0.61) DGKALMNAPAMCES2CES1
SCHEMBL8645409 1.00 DGKA (0.61) DGKALMNAPAMCES2CES1
SCHEMBL4288902 1.00 DGKA (0.61) DGKALMNAPAMCES2CES1
SCHEMBL28057936 1.00 DGKA (0.61) DGKALMNAPAMCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023118230-A2 COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER WITH A LONG HYDROCARBON-BASED CHAIN BEARING IONIC GROUP(S), AND METHOD FOR TREATING KERATIN MATERIALS USING THE COMPOSITION L'OREAL (FR) 2023-06-29 WO disclosed
US-11066351-B2 Organic compound, three-dimensional organic framework formed by using organic compound, separation sieve and optical layer, which comprise organic framework, and optical device comprising optical layer as optical amplification layer IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) 2021-07-20 US disclosed
EP-3810570-A1 SOLID SUPPORT Novartis AG (CH) 2021-04-28 EP disclosed
EP-3655426-A1 EGF(A) ANALOGUES, PREPARATION, FORMULATIONS AND USES THEREOF Novo Nordisk A/S (DK) 2020-05-27 EP disclosed
EP-3612539-A1 PHOSPHONIUM-ION TETHERED TETRACYCLINE DRUGS FOR TREATMENT OF CANCER Rising Tide Foundation (CH) 2020-02-26 EP disclosed
WO-2020036151-A1 SEPARATING MATERIAL, METHOD OF MANUFACTURING SEPARATING MATERIAL, AND COLUMN 日立化成株式会社 2020-02-20 WO disclosed
WO-2019234228-A1 BETA-AMINO-ALPHA-HYDROXYALKYLPHENYL DERIVATIVES AND THEIR USE FOR CANCER TREATMENT RISING TIDE FOUNDATION (CH) 2019-12-12 WO disclosed
US-20190031586-A1 ORGANIC COMPOUND, THREE-DIMENSIONAL ORGANIC FRAMEWORK FORMED BY USING ORGANIC COMPOUND, SEPARATION SIEVE AND OPTICAL LAYER, WHICH COMPRISE ORGANIC FRAMEWORK, AND OPTICAL DEVICE COMPRISING OPTICAL LAYER AS OPTICAL AMPLIFICATION LAYER INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2019-01-31 US disclosed
WO-2019016300-A1 EGF(A) ANALOGUES, PREPARATION, FORMULATIONS AND USES THEREOF NOVO NORDISK A/S (DK) 2019-01-24 WO disclosed
WO-2018193113-A1 PHOSPHONIUM-ION TETHERED TETRACYCLINE DRUGS FOR TREATMENT OF CANCER NOVINTUM BIOTECHNOLOGY GMBH (CH) 2018-10-25 WO disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
WO-1999029640-A2 COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR EISAI CO., LTD. (JP) 1999-06-17 WO disclosed
US-5840493-A DIAGNOSIS OF LATE ONSET DIABETES BY DETECTION OF MUTATIONS IN ADENOSINE TRIPHOSPHATE SYNTHASE OR TRANSFER RNA (LYS) GENES IN A BIOLOGICAL SAMPLE; LABELLED NUCLEOTIDE SEQUENCES AS DETECTORS; ACCURACY MITOKOR (US) 1998-11-24 US disclosed
EP-0858473-A1 LIQUID CRYSTAL POLYMERS THE SECRETARY OF STATE FOR DEFENCE (GB) 1998-08-19 EP disclosed
WO-1997016471-A1 LIQUID CRYSTAL POLYMERS THE SECRETARY OF STATE FOR DEFENCE (GB) 1997-05-09 WO disclosed
EP-0746557-A4 INTRACELLULAR SIGNALLING MEDIATORS CELL THERAPEUTICS INC (US) 1997-05-02 EP disclosed
EP-0746557-A1 INTRACELLULAR SIGNALLING MEDIATORS CELL THERAPEUTICS, INC. (US) 1996-12-11 EP disclosed
WO-1995022546-A1 INTRACELLULAR SIGNALLING MEDIATORS CELL THERAPEUTICS, INC. (US) 1995-08-24 WO disclosed
EP-0015824-B1 METAL DITHIOPHOSPHATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ADDITIVES FOR LUBRICATING OILS OROGIL (FR) 1982-02-17 EP disclosed
EP-0015824-A1 Metal dithiophosphates, process for their preparation and their use as additives for lubricating oils OROGIL (FR) 1980-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11066351-B2 Organic compound, three-dimensional organic framework formed by using organic compound, separation sieve and optical layer, which comprise organic framework, and optical device comprising optical layer as optical amplification layer OR10J3, POF1B, ORC3 DGKA 2494/4885LMNA 2924/4885PAM 1097/4885
US-20190031586-A1 ORGANIC COMPOUND, THREE-DIMENSIONAL ORGANIC FRAMEWORK FORMED BY USING ORGANIC COMPOUND, SEPARATION SIEVE AND OPTICAL LAYER, WHICH COMPRISE ORGANIC FRAMEWORK, AND OPTICAL DEVICE COMPRISING OPTICAL LAYER AS OPTICAL AMPLIFICATION LAYER OR10J3, POF1B, ORC3 DGKA 2494/4885LMNA 2924/4885PAM 1097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.