SCHEMBL3981071

SCHEMBL3981071

O=C1C=C(Cl)C(=Nc2ccc(O)cc2)C(Cl)=C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 2/20 0.35
▸ ESR2 Q92731 2/20 0.35
▸ GFER P55789 1/20 0.35
▸ SYK P43405 1/20 0.35
▸ S100B P04271 1/20 0.34
▸ MAPT P10636 4/20 0.34
▸ KDM4E B2RXH2 2/20 0.34
▸ L3MBTL1 Q9Y468 2/20 0.34
▸ GSK3B P49841 1/20 0.34
▸ THRB P10828 1/20 0.34
▸ PKM P14618 1/20 0.34
▸ BLM P54132 1/20 0.34
▸ PLEC Q15149 1/20 0.34
▸ MEN1 O00255 3/20 0.33
▸ KMT2A Q03164 3/20 0.33
▸ CA12 O43570 3/20 0.33
▸ CA2 P00918 3/20 0.33
▸ CA9 Q16790 3/20 0.33
▸ CA1 P00915 2/20 0.33
▸ TXNRD1 Q16881 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31213284 0.98 CA12 (0.34) ESR1ESR2GFERSYKS100B
SCHEMBL11081291 0.80 SYK (0.33) ESR1ESR2GFERSYKS100B
SCHEMBL11318039 0.77 MAPT (0.43) ESR2GFERS100BMAPTKDM4E
SCHEMBL107238 0.73 TXNRD1 (0.37) ESR1ESR2GFERS100BMAPT
SCHEMBL3788216 0.72 ESR1 (0.35) ESR1ESR2GFERSYKMAPT
SCHEMBL505621 0.72 TXNRD1 (0.36) ESR1ESR2GFERS100BMAPT
Water SCHEMBL3454312 0.70 TXNRD1 (0.35) ESR1ESR2GFERS100BMAPT
SCHEMBL7169572 0.70 CA12 (0.33) ESR1ESR2GFERS100BMAPT
Water SCHEMBL28299335 0.70 TXNRD1 (0.35) ESR1ESR2GFERS100BMAPT
SCHEMBL11119934 0.69 TXNRD1 (0.41) ESR1ESR2GFERS100BMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1271143-B1 Test strip having a porous filter layer ARKRAY INC (JP) 2009-05-06 — — EP disclosed
US-7201871-B2 Specimen having capability of separating solid component ARKRAY INC. (JP) 2007-04-10 — — US disclosed
US-7189576-B2 Method for measuring substance and testing piece ARKRAY INC. (JP) 2007-03-13 — — US disclosed
US-7153696-B2 Method for measuring substance and testing piece ARKRAY INC. (JP) 2006-12-26 — — US disclosed
US-7098038-B2 Method for measuring substance and testing piece ARKRAY INC. (JP) 2006-08-29 — — US disclosed
EP-0860695-B1 Method for measuring an analyte and corresponding device ARKRAY INC (JP) 2006-01-04 — — EP disclosed
US-6777243-B2 MEASURING DETECTABLE SUBSTANCE BY USING AQUEOUS REACTION SYSTEM INCLUDING FORMATION REACTION OF DETECTABLE SUBSTANCE BASED ON CHEMICAL REACTION OF ANALYTE CONTAINED IN SAMPLE; REACTING IN PRESENCE OF LAYERED INORGANIC COMPOUND ARKRAY INC. (JP) 2004-08-17 — — US disclosed
US-20030203503-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-10-30 — — US disclosed
US-20030180183-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-25 — — US disclosed
US-20030175985-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-18 — — US disclosed
US-20030175984-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-18 — — US disclosed
US-20030166295-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-04 — — US disclosed
US-20030044316-A1 Specimen having capability of separating solid component ARKRAY INC. (JP) 2003-03-06 — — US disclosed
EP-1271143-A1 SPECIMEN HAVING CAPABILITY OF SEPARATING SOLID COMPONENT ARKRAY, Inc. (JP) 2003-01-02 — — EP disclosed
EP-0860695-A9 METHOD OF MEASUREMENT OF MATERIAL AND TESTPIECE KABUSHIKI KAISHA KYOTO DAIICHI KAGAKU (JP) 2001-10-17 — — EP disclosed
EP-0860695-A1 METHOD OF MEASUREMENT OF MATERIAL AND TESTPIECE KABUSHIKI KAISHA KYOTO DAIICHI KAGAKU (JP) 1998-08-26 — — EP disclosed
US-5790627-A Method and apparatus for observing a specimen using an X-ray microscope RESEARCH DEVELOPMENT CORP. (JP) 1998-08-04 — — US disclosed
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