SCHEMBL107238

SCHEMBL107238

O=C1C(Cl)=CC(=Nc2ccc(O)cc2)C=C1Cl

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TXNRD1 Q16881 1/20 0.37
TXNRD3 Q86VQ6 1/20 0.37
TXNRD2 Q9NNW7 1/20 0.37
CA12 O43570 3/20 0.35
CA2 P00918 3/20 0.35
CA9 Q16790 3/20 0.35
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
CA7 P43166 1/20 0.35
GFER P55789 1/20 0.35
S100B P04271 1/20 0.34
CA1 P00915 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
KMT2A Q03164 1/20 0.33
AURKA O14965 1/20 0.33
AURKB Q96GD4 1/20 0.33
MAPT P10636 1/20 0.32
SENP1 Q9P0U3 1/20 0.32
GLB1 P16278 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL505621 0.98 TXNRD1 (0.36) TXNRD1TXNRD3TXNRD2CA12CA2
Water SCHEMBL28299335 0.96 TXNRD1 (0.35) TXNRD1TXNRD3TXNRD2CA12CA2
Water SCHEMBL3454312 0.96 TXNRD1 (0.35) TXNRD1TXNRD3TXNRD2CA12CA2
SCHEMBL16310730 0.82 ALDH1A1 (0.33) TXNRD1TXNRD3TXNRD2MAPK1
SCHEMBL11119934 0.80 TXNRD1 (0.41) TXNRD1TXNRD3TXNRD2CA12CA2
SCHEMBL505620 0.79
SCHEMBL3132789 0.79 PTGS1 (0.46) TXNRD1TXNRD3TXNRD2CA2ESR1
Water SCHEMBL4107444 0.78
SCHEMBL8954156 0.78 PTGS1 (0.45) TXNRD1TXNRD3TXNRD2CA2ESR1
SCHEMBL1783165 0.77 MAPT (0.38) TXNRD1CA12CA2CA9ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2647 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12625082-B2 Optical detection chip and optical detection system THE UNIVERSITY OF KITAKYUSHU (JP) 2026-05-12 US claimed
EP-4677353-A1 SYSTEM FOR LABEL-FREE ELECTROCHEMICAL SENSING President And Fellows Of Harvard College (US) 2026-01-14 EP claimed
US-20240344997-A1 OPTICAL DETECTION CHIP AND OPTICAL DETECTION SYSTEM TOYOKO KAGAKU CO., LTD. (JP) 2024-10-17 US claimed
WO-2024197225-A1 REDOX ACTIVE ANTIFOULING COATINGS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-09-26 WO claimed
WO-2024191912-A1 SYSTEM FOR LABEL-FREE ELECTROCHEMICAL SENSING PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-09-19 WO claimed
EP-4386375-A1 OPTICAL DETECTION CHIP AND OPTICAL DETECTION SYSTEM The University of Kitakyushu (JP) 2024-06-19 EP claimed
WO-2024119224-A1 ELECTROCHEMICAL CELL AND USES THEREOF AUSTRALIAN NATIONAL UNIVERSITY (AU) 2024-06-13 WO claimed
CN-115060663-B Method for quantitatively testing banana quality based on machine learning 中新国际联合研究院 2024-04-19 CN claimed
CN-117813500-A Optical detection chip and optical detection system 公立大学法人北九州市立大学 2024-04-02 CN claimed
EP-4308111-A1 REDOX-ACTIVE COMPOUND FOR USE IN THE METHOD FOR TREATING DISEASES DUE TO DYSFUNCTION OF THE MITOCHONDRIAL RESPIRATORY CHAIN COMPLEXES I, II, III Università degli Studi di Padova (IT) 2024-01-24 EP claimed
EP-0293732-A2 Simultaneous assay for glucose and urea ABBOTT LABORATORIES (US) 1988-12-07 EP claimed
WO-1988008037-A1 METHOD FOR THE DETECTION OF BACTERIA AND FUNGI CAMBRIDGE BIOSCIENCE CORPORATION (US) 1988-10-20 WO claimed
WO-1988001299-A1 METHOD AND APPARATUS FOR DETECTING GASEOUS COMPOUNDS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1988-02-25 WO claimed
EP-0255291-A1 Method and apparatus for electrochemical measurements UNILEVER PLC (GB) 1988-02-03 EP claimed
US-4704358-A Δ1 -dehydrogenation with heat or air-dried B. cyclooxidans THE UPJOHN COMPANY (US) 1987-11-03 US claimed
EP-0079703-B1 CURING COMPOSITIONS Lingner + Fischer GmbH (DE) 1986-09-10 EP claimed
EP-0114267-B1 TEST SYSTEM AND METHOD FOR THE DETERMINATION OF NAD(P)H MERCK PATENT GmbH (DE) 1986-06-25 EP claimed
US-4524134-A BIOCONVERSION WITH ARTHROBACTER SIMPLEX THE UPJOHN COMPANY (US) 1985-06-18 US claimed
US-4467079-A UNSATURATED MONOMER, POLYMERIZATION CATALYSTS LINGNER & FISCHER GMBH (DE) 1984-08-21 US claimed
EP-0079703-A1 Curing compositions Lingner + Fischer GmbH (DE) 1983-05-25 EP claimed