Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4098217 | 0.92 | SERPINE1 (0.50) | SERPINE1ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL3983400 | 0.91 | SERPINE1 (0.49) | SERPINE1ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL3982591 | 0.88 | SERPINE1 (0.50) | SERPINE1ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL3988840 | 0.87 | SERPINE1 (0.46) | SERPINE1ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL3983573 | 0.87 | SERPINE1 (0.51) | SERPINE1ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL3981129 | 0.85 | SERPINE1 (0.46) | SERPINE1ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL3983571 | 0.84 | SERPINE1 (0.45) | SERPINE1ALDH1A1CYP1A2POLBCYP2D6 | |
| SCHEMBL3948702 | 0.83 | BRD4 (0.50) | SERPINE1ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL3985810 | 0.83 | SERPINE1 (0.49) | SERPINE1ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL3986748 | 0.82 | SERPINE1 (0.47) | SERPINE1ALDH1A1KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888058-B1 | INHIBITORS OF SOLUBLE ADENYLATE CYCLASE | BAYER SCHERING PHARMA AG (DE) | 2009-05-20 | — | — | EP | claimed |