Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TACR2 | P21452 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3983571 | 0.96 | SERPINE1 (0.45) | SERPINE1ALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3983700 | 0.88 | LMNA (0.48) | SERPINE1ALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4098217 | 0.86 | SERPINE1 (0.50) | SERPINE1ALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3982797 | 0.85 | ALDH1A1 (0.48) | SERPINE1ALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3983400 | 0.85 | SERPINE1 (0.49) | SERPINE1ALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3941985 | 0.85 | ALDH1A1 (0.46) | SERPINE1ALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3981944 | 0.85 | SERPINE1 (0.49) | SERPINE1ALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3983675 | 0.84 | ALDH1A1 (0.46) | SERPINE1ALDH1A1CA1CA2CA9 | |
| SCHEMBL3988840 | 0.84 | SERPINE1 (0.46) | SERPINE1ALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3982486 | 0.83 | SERPINE1 (0.45) | SERPINE1ALDH1A1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888058-B1 | INHIBITORS OF SOLUBLE ADENYLATE CYCLASE | BAYER SCHERING PHARMA AG (DE) | 2009-05-20 | — | — | EP | claimed |