SCHEMBL3981999

SCHEMBL3981999

Oc1ccnc(-c2ccccn2)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.50
LMNA P02545 3/20 0.50
CCR1 P32246 3/20 0.50
CCR5 P51681 3/20 0.50
CCR8 P51685 3/20 0.50
CYP1A2 P05177 1/20 0.50
POLB P06746 1/20 0.50
METAP1 P53582 1/20 0.50
BLM P54132 1/20 0.50
HIF1A Q16665 1/20 0.50
DOHH Q9BU89 1/20 0.50
P4HTM Q9NXG6 1/20 0.50
NPC1 O15118 6/20 0.43
RAB9A P51151 5/20 0.43
TP53 P04637 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
ALOX15 P16050 2/20 0.43
HTT P42858 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL4910474 0.84 KDM4E (0.41) KDM4ELMNACCR1CCR5CCR8
SCHEMBL4657861 0.84 KDM4E (0.50) KDM4ELMNACCR1CCR5CCR8
SCHEMBL8546751 0.84 KDM4E (0.42) KDM4ELMNACCR1CCR5CCR8
SCHEMBL28453174 0.81 KDM4E (0.49) KDM4ELMNACCR1CCR5CCR8
SCHEMBL28449259 0.81 KDM4E (0.53) KDM4ELMNACCR1CCR5CCR8
SCHEMBL2573127 0.79 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
SCHEMBL30570543 0.79 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
SCHEMBL21647242 0.78 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL31134104 0.78 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
Lithium SCHEMBL29809836 0.78 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116102725-B Preparation method of flame-retardant polycarbonate polyol 万华化学集团股份有限公司 2025-04-01 CN claimed
CN-118307600-A Catalyst, preparation method thereof and method for co-producing bio-based 1, 3-propanediol and 1, 3-dihydroxyacetone by using catalyst 北京旭阳科技有限公司 2024-07-09 CN claimed
CN-118272031-A Adhesive for improving compressive strength of ultrathin stone 山东华诚高科胶粘剂有限公司 2024-07-02 CN claimed
CN-117466625-A Compounding process of carbon ceramic brake disc compounded with carbon fibers 烟台美丰机械集团有限公司 2024-01-30 CN claimed
CN-114478970-B Precursor composition of covalent organic framework material and application thereof 中国科学院大连化学物理研究所 2023-11-03 CN claimed
CN-116554520-B Polyethylene composite plastic film containing europium light conversion agent and preparation process thereof 淄博益久塑胶有限公司 2023-09-01 CN claimed
CN-116554520-A Polyethylene composite plastic film containing europium light conversion agent and preparation process thereof 淄博益久塑胶有限公司 2023-08-08 CN claimed
CN-116496466-A Polyurethane material and preparation method thereof 中国科学院兰州化学物理研究所 2023-07-28 CN claimed
CN-116163054-B High-elasticity breathable three-dimensional knitwear fabric and preparation method thereof 比音勒芬服饰股份有限公司 2023-06-16 CN claimed
CN-116163054-A High-elasticity breathable three-dimensional knitwear fabric and preparation method thereof 比音勒芬服饰股份有限公司 2023-05-26 CN claimed
CN-116102725-A Preparation method of flame-retardant polycarbonate polyol 万华化学集团股份有限公司 2023-05-12 CN claimed
CN-114478970-A Precursor composition of covalent organic framework material and application thereof 中国科学院大连化学物理研究所 2022-05-13 CN claimed
CN-110343240-B Palladium-containing organic porous polymer and preparation method and application thereof 湖北大学 2021-11-09 CN claimed
CN-111825843-B Method for synthesizing partially renewable polysiloxanes by catalytic dehydrogenation coupling of ionic iridium complex 中国科学院大连化学物理研究所 2021-08-31 CN claimed
CN-111825843-A Method for synthesizing partially renewable polysiloxanes by catalytic dehydrogenation coupling of ionic iridium complex 中国科学院大连化学物理研究所 2020-10-27 CN claimed
US-20070185072-A1 Nitrogeneous polycyclic derivatives useful as chelators of metal ions and their applications CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2007-08-09 US claimed
EP-1606292-A2 NITROGENEOUS POLYCYCLIC DERIVATIVES USEFUL AS CHELATORS OF METAL IONS AND THEIR APPLICATIONS Palumed SA (FR) 2005-12-21 EP claimed
WO-2004083215-A9 NITROGENEOUS POLYCYCLIC DERIVATIVES USEFUL AS CHELATORS OF METAL IONS AND THEIR APPLICATIONS PALUMED SA (FR) 2004-12-23 WO claimed
WO-2004083215-A2 NITROGENEOUS POLYCYCLIC DERIVATIVES USEFUL AS CHELATORS OF METAL IONS AND THEIR APPLICATIONS PALUMED SA (FR) 2004-09-30 WO claimed
WO-1992014741-A1 MONO, BIS OR TRIS (2,2'-SUBSTITUTED BIPYRIDINE) COMPLEXES OF A METAL SELECTED AMONGST IRON, RUTHENIUM, OSMIUM OR VANADIUM AND PREPARATION METHODS THEREOF ASULAB S.A. (CH) 1992-09-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070185072-A1 Nitrogeneous polycyclic derivatives useful as chelators of metal ions and their applications NLN, PSEN2, SLC30A6 KDM4E 1861/4885LMNA 2826/4885CCR1 4126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.