Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | CCR8 | P51685 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31563654 | 0.84 | KDM4E (0.46) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL30144092 | 0.84 | KDM4E (0.46) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL3981999 | 0.84 | KDM4E (0.50) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL31663480 | 0.81 | CYP2A6 (0.39) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL30031 | 0.78 | KDM4E (0.56) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL5463849 | 0.77 | KDM4E (0.50) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL4755586 | 0.77 | KDM1A (0.48) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL16241819 | 0.76 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL78140 | 0.76 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL15436287 | 0.76 | KDM4E (0.54) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624097-B1 | TARGETING RADIOACTIVE IMMUNOREAGENTS | NYCOMED IMAGING AS (NO) | 1998-03-18 | — | — | EP | disclosed |
| US-5707603-A | Pyridine complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions | NYCOMED IMAGING AS (NO) | 1998-01-13 | — | — | US | disclosed |
| EP-0639083-A1 | COMPLEXING AGENTS AND TARGETING IMMUNOREAGENTS | NYCOMED IMAGING AS (NO) | 1995-02-22 | — | — | EP | disclosed |
| US-5367080-A | PYRIDINE DERIVATIVES | STERLING WINTHROP INC. (US) | 1994-11-22 | — | — | US | disclosed |
| EP-0624097-A1 | TARGETING RADIOACTIVE IMMUNOREAGENTS | NYCOMED IMAGING AS (NO) | 1994-11-17 | — | — | EP | disclosed |
| WO-1993021957-A1 | COMPLEXING AGENTS AND TARGETING IMMUNOREAGENTS | STERLING WINTHROP INC. (US) | 1993-11-11 | — | — | WO | disclosed |
| WO-1992008494-A2 | TARGETING RADIOACTIVE IMMUNOREAGENTS | STERLING WINTHROP INC. (US) | 1992-05-29 | — | — | WO | disclosed |