Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | BCL9 | O00512 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27584718 | 1.00 | ALDH1A1 (0.50) | ALDH1A1LMNACES2CES1HDAC3 | |
| SCHEMBL17923927 | 0.98 | ALDH1A1 (0.48) | ALDH1A1LMNACES2CES1HDAC3 | |
| SCHEMBL5903188 | 0.85 | LMNA (0.52) | ALDH1A1LMNACES2CES1TSHR | |
| SCHEMBL28704382 | 0.83 | LMNA (0.66) | ALDH1A1LMNACES2CES1TSHR | |
| SCHEMBL5903335 | 0.83 | LMNA (0.66) | ALDH1A1LMNACES2CES1TSHR | |
| SCHEMBL5903326 | 0.83 | LMNA (0.66) | ALDH1A1LMNACES2CES1TSHR | |
| SCHEMBL2475707 | 0.83 | ALDH1A1 (0.38) | ALDH1A1LMNACES2CES1HDAC3 | |
| SCHEMBL28891600 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNACES2CES1HDAC3 | |
| SCHEMBL27315597 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNACES2CES1HDAC3 | |
| SCHEMBL124651 | 0.81 | ALDH1A1 (0.37) | ALDH1A1LMNACES2CES1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101677-B2 | Multi-component room-temperature-curable silicone rubber composition | DOW CORNING TORAY COMPANY, LTD. (JP) | 2012-01-24 | — | — | US | disclosed |
| US-20090281222-A1 | Multi-Component Room-Temperature-Curable Silicone Rubber Composition | DOW CORNING TORAY COMPANY, LTD. (JP) | 2009-11-12 | — | — | US | disclosed |