Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28329003 | 0.83 | ALDH1A1 (0.35) | TSHRALDH1A1 | |
| Methylamine SCHEMBL4754517 | 0.83 | ALDH1A1 (0.36) | TSHRALDH1A1 | |
| Methylamine SCHEMBL4277615 | 0.83 | ALDH1A1 (0.36) | TSHRALDH1A1 | |
| SCHEMBL28579725 | 0.82 | SMN1; SMN2 (0.37) | TSHRALDH1A1 | |
| SCHEMBL4842705 | 0.80 | LMNA (0.33) | — | |
| 2-Methoxyethanol SCHEMBL14977385 | 0.78 | TSHR (0.34) | TSHRALDH1A1 | |
| SCHEMBL8389324 | 0.78 | ALDH1A1 (0.39) | TSHRALDH1A1 | |
| SCHEMBL28858270 | 0.78 | LMNA (0.31) | — | |
| SCHEMBL4320822 | 0.78 | LMNA (0.32) | — | |
| Ethylene Glycol SCHEMBL11555178 | 0.77 | LMNA (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008149375-A1 | IMPROVED ORGANOSILICON COMPOUNDS | RANKA, SEEMA, AJAY (IN) | 2008-12-11 | — | — | WO | claimed |
| US-20080009644-A1 | Organosilicon Compounds | ZYDEX INDUSTRIES | 2008-01-10 | — | — | US | claimed |
| US-7553983-B2 | Organosilicon compounds | ZYDEX INDUSTRIES (IN) | 2009-06-30 | — | — | US | disclosed |
| WO-2008149375-A1 | IMPROVED ORGANOSILICON COMPOUNDS | RANKA, SEEMA, AJAY (IN) | 2008-12-11 | — | — | WO | disclosed |
| US-20080009644-A1 | Organosilicon Compounds | ZYDEX INDUSTRIES | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009644-A1 | Organosilicon Compounds | CUL1, CUL3, MGAM | TSHR 4731/4885ALDH1A1 1076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.