SCHEMBL398247

SCHEMBL398247

CCCCCCCCc1c(CC)nc2nc(N)nn2c1N

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 4/20 0.35
TLR7 Q9NYK1 1/20 0.35
GCGR P47871 1/20 0.35
ALDH1A1 P00352 4/20 0.33
DHFR P00374 2/20 0.33
GAA P10253 1/20 0.32
KDM4E B2RXH2 4/20 0.32
HPGD P15428 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CHEK1 O14757 1/20 0.30
MET P08581 1/20 0.30
LTK P29376 1/20 0.30
CDK9 P50750 1/20 0.30
PRKX P51817 1/20 0.30
LRRK2 Q5S007 1/20 0.30
CLK4 Q9HAZ1 1/20 0.30
BRD4 O60885 1/20 0.30
HSP90AB1 P08238 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5091103 0.90 GCGR (0.35) TLR8TLR7GCGRALDH1A1DHFR
SCHEMBL5091098 0.90 GCGR (0.35) TLR8TLR7GCGRALDH1A1DHFR
SCHEMBL5095240 0.88 GCGR (0.36) TLR8TLR7GCGRALDH1A1GAA
SCHEMBL5009134 0.86 GCGR (0.33) TLR8TLR7GCGRALDH1A1DHFR
SCHEMBL3135629 0.78 GAA (0.45) GAASMN1; SMN2
SCHEMBL3121971 0.78 GAA (0.45) GAASMN1; SMN2
SCHEMBL174682 0.78 GAA (0.45) GAASMN1; SMN2
SCHEMBL3132086 0.78 GAA (0.45) GAASMN1; SMN2
SCHEMBL3125386 0.78 GAA (0.45) GAASMN1; SMN2
SCHEMBL3138084 0.76 GAA (0.43) GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3954214-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS Agrivalle Brasil Industria e Comércio de Produtos Agrícolas Ltda (BR) 2022-02-16 EP claimed
EP-3240421-A1 MICROBIAL COMPOSITIONS FOR USE IN COMBINATION WITH SOIL INSECTICIDES FOR BENEFITING PLANT GROWTH FMC Corporation (US) 2017-11-08 EP claimed
EP-3240406-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION (US) 2017-11-08 EP claimed
US-20170215418-A1 Controlling Red Rice with Mesotrione FMC CORP (US) 2017-08-03 US claimed
US-20170196226-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2017-07-13 US claimed
US-9635854-B2 Controlling red rice with mesotrione FMC CORPORATION (US) 2017-05-02 US claimed
US-9622484-B2 Microbial compositions and methods of use for benefiting plant growth and treating plant disease FMC CORPORATION (US) 2017-04-18 US claimed
WO-2016108972-A1 MICROBIAL COMPOSITIONS FOR USE IN COMBINATION WITH SOIL INSECTICIDES FOR BENEFITING PLANT GROWTH FMC CORPORATION (US) 2016-07-07 WO claimed
WO-2016109332-A1 COMPOSITIONS AND METHODS FOR USE OF INSECTICIDE WITH BACILLUS SP. D747 FMC CORPORATION (US) 2016-07-07 WO claimed
WO-2016109396-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION (US) 2016-07-07 WO claimed
US-20160183538-A1 MICROBIAL COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2016-06-30 US claimed
US-20160186273-A1 BACILLUS AMYLOLIQUEFACIENS RTI301 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2016-06-30 US claimed
US-20160183537-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2016-06-30 US claimed
US-8461077-B2 Combinations of active substances BASF SE (DE) 2013-06-11 US claimed
US-20100197741-A1 Ternary Fungicidal Compositions Comprising Boscalid and Chlorothalonil BASF SE (DE) 2010-08-05 US claimed
EP-2205082-A1 TERNARY FUNGICIDAL COMPOSITIONS COMPRISING BOSCALID AND CHLOROTHALONIL BASF SE (DE) 2010-07-14 EP claimed
US-20100105557-A1 Combinations of Active Substances BASF SE (DE) 2010-04-29 US claimed
WO-2009040397-A1 TERNARY FUNGICIDAL COMPOSITIONS COMPRISING BOSCALID AND CHLOROTHALONIL BASF SE (DE) 2009-04-02 WO claimed
CN-122094561-A Liquid fertilizer ready-to-use agrochemical formulation 2026-05-26 CN disclosed
WO-2007012598-A1 FUNGICIDAL MIXTURES BASED ON AZOLOPYRIMIDINYLAMINES BASF AKTIENGESELLSCHAFT (DE) 2007-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160186273-A1 BACILLUS AMYLOLIQUEFACIENS RTI301 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE BTF3, MYB, AGXT TLR8 1347/4885TLR7 3311/4885GCGR 2059/4885
US-20170196226-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE MYB, BTF3, NRDC TLR8 2026/4885TLR7 2793/4885GCGR 2641/4885
US-20100197741-A1 Ternary Fungicidal Compositions Comprising Boscalid and Chlorothalonil CBR3, CBX3, BRD3 TLR8 4882/4885TLR7 4863/4885GCGR 3800/4885
US-20100105557-A1 Combinations of Active Substances AGXT, PAM, CUL3 TLR8 1546/4885TLR7 1238/4885GCGR 1663/4885
US-20160183537-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE MYB, BTF3, NRDC TLR8 2026/4885TLR7 2793/4885GCGR 2641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.