⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26014 | 1.00 | — | — | |
| SCHEMBL13626153 | 0.86 | — | — | |
| SCHEMBL1270703 | 0.86 | — | — | |
| SCHEMBL1270704 | 0.86 | — | — | |
| SCHEMBL3901539 | 0.84 | FAAH (0.65) | — | |
| SCHEMBL3901535 | 0.84 | FAAH (0.65) | — | |
| SCHEMBL17352280 | 0.82 | FAAH (0.69) | — | |
| SCHEMBL8696497 | 0.82 | FAAH (0.69) | — | |
| SCHEMBL8696500 | 0.82 | FAAH (0.69) | — | |
| SCHEMBL17352281 | 0.82 | FAAH (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018102261-A2 | BORONIC DERIVATIVES HYDROXAMATES AS ANTICANCER AGENTS | XAVIER UNIVERSITY OF LOUISIANA (US) | 2018-06-07 | — | — | WO | claimed |
| US-5679831-A | Process for the preparation of an ester | DSM N.V. (NL) | 1997-10-21 | — | — | US | claimed |
| US-20230129262-A1 | METHODS AND PHARMACEUTICAL COMPOSITIONS OF THROMBOXANE A2 RECEPTOR ANTAGONIST FOR THE TREATMENT OF COVID-19 | OGLETREE MARTIN (US) | 2023-04-27 | — | — | US | disclosed |
| EP-4125882-A1 | METHODS AND PHARMACEUTICAL COMPOSITIONS OF THROMBOXANE A2 RECEPTOR ANTAGONIST FOR THE TREATMENT OF COVID-19 | Ogletree, Martin (US) | 2023-02-08 | — | — | EP | disclosed |
| CN-115666560-A | Methods and pharmaceutical compositions for treating thromboxane A2 receptor antagonists of COVID-19 | 马丁·奥格特树 | 2023-01-31 | — | — | CN | disclosed |
| CN-115624549-A | Compositions and methods for treating muscular dystrophy using thromboxane-A2 receptor antagonists | 坎伯兰医药品股份有限公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-109152767-B | Compositions and methods for treating muscular dystrophy using thromboxane-A2 receptor antagonists | 坎伯兰医药品股份有限公司 | 2022-10-21 | — | — | CN | disclosed |
| US-20220211674-A1 | Thromboxane Receptor Antagonists in AERD/Asthma | CUMBERLAND PHARMACEUTICALS INC. (US) | 2022-07-07 | — | — | US | disclosed |
| WO-2020161072-A1 | PROCESS FOR MANUFACTURING QUANTUM DOTS | UNIVERSITEIT VAN AMSTERDAM (NL) | 2020-08-13 | — | — | WO | disclosed |
| EP-3693439-A1 | METHOD FOR MANUFACTURING QUANTUM DOTS | Universiteit van Amsterdam (NL) | 2020-08-12 | — | — | EP | disclosed |
| EP-3601228-A1 | MICROBIOCIDAL QUINOLINE (THIO)CARBOXAMIDE DERIVATIVES | Syngenta Participations AG (CH) | 2020-02-05 | — | — | EP | disclosed |
| WO-2013185928-A1 | METHOD FOR THE PREPARATION OF 1-ARYL-1-ALKYL-2-ALKYL-3-DIALKYLAMINOPROPANE COMPOUNDS | SIEGFRIED AG (CH) | 2013-12-19 | — | — | WO | disclosed |
| EP-2056798-A2 | SORBIC ACID ANALOG CO-CRYSTALS | Amgen, Inc (US) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008024437-A2 | SORBIC ACID ANALOG CO-CRYSTALS | AMGEN INC. (US) | 2008-02-28 | — | — | WO | disclosed |
| US-20080051453-A1 | Sorbic acid analog co-crystals | AMGEN INC. | 2008-02-28 | — | — | US | disclosed |
| EP-1346377-A1 | ELECTRICAL CABLE, PARTICULARLY FOR HIGH VOLTAGE DIRECT CURRENT TRANSMISSION OR DISTRIBUTION, AND INSULATING COMPOSITION | PIRELLI S.p.A. (IT) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002052582-A1 | ELECTRICAL CABLE, PARTICULARLY FOR HIGH VOLTAGE DIRECT CURRENT TRANSMISSION OR DISTRIBUTION, AND INSULATING COMPOSITION | PIRELLI S.P.A. (IT) | 2002-07-04 | — | — | WO | disclosed |
| EP-0662467-B1 | Process for the preparation of an ester | DSM NV (NL) | 1998-05-06 | — | — | EP | disclosed |
| US-5679831-A | Process for the preparation of an ester | DSM N.V. (NL) | 1997-10-21 | — | — | US | disclosed |
| EP-0662467-A1 | Process for the preparation of an ester | DSM N.V. (NL) | 1995-07-12 | — | — | EP | disclosed |