Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 8/20 | 0.32 |
| ▸ | THRB | P10828 | 8/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979489 | 0.86 | EGLN1 (0.39) | THRATHRBEGLN1 | |
| SCHEMBL3975144 | 0.86 | THRB (0.37) | THRATHRB | |
| SCHEMBL4299054 | 0.86 | THRA (0.38) | THRATHRB | |
| SCHEMBL3979612 | 0.84 | THRA (0.40) | THRATHRBEGLN1 | |
| SCHEMBL4297760 | 0.72 | THRB (0.37) | THRATHRB | |
| SCHEMBL3981706 | 0.72 | THRA (0.39) | THRATHRB | |
| SCHEMBL3985944 | 0.72 | THRA (0.39) | THRATHRB | |
| SCHEMBL3981701 | 0.72 | THRA (0.39) | THRATHRB | |
| SCHEMBL4531287 | 0.71 | MEN1 (0.47) | THRATHRB | |
| SCHEMBL4299290 | 0.71 | THRA (0.36) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024336-A1 | NOVEL PHARMACEUTICAL COMPOSITIONS | KARO BIO AB (SE) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007128492-A1 | NOVEL PHARMACEUTICAL COMPOSITIONS | KARO BIO AB (SE) | 2007-11-15 | — | — | WO | disclosed |