Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | VHL | P40337 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4097506 | 0.86 | GPR119 (0.57) | GPR119TP53 | |
| SCHEMBL3983572 | 0.85 | NPC1 (0.37) | LTA4HCXCR4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3981387 | 0.84 | GPR119 (0.44) | GPR119MTOR | |
| SCHEMBL3984090 | 0.84 | CXCR4 (0.42) | CXCR4RAB9ANPC1SMN1; SMN2DRD4 | |
| SCHEMBL3985778 | 0.84 | NPC1 (0.42) | CXCR4GPR119RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3980490 | 0.81 | CYP4F2 (0.51) | GPR119 | |
| SCHEMBL3984556 | 0.78 | KDM1A (0.47) | CXCR4DRD4HPGDSPDCD1CD274 | |
| SCHEMBL3983774 | 0.77 | GPR119 (0.41) | GPR119HPGDSMTORVHLHTR5A | |
| SCHEMBL3984528 | 0.77 | GPR119 (0.49) | GPR119MAPTHPGDSKMT2ATP53 | |
| SCHEMBL3985988 | 0.76 | KDM1A (0.48) | CXCR4KDM4EMAPTDRD4TEAD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059516-A1 | PYRIDINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (publ) (SE) | 2009-05-20 | — | — | EP | disclosed |
| WO-2008025798-A1 | PYRIDINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2008-03-06 | — | — | WO | disclosed |