SCHEMBL3983585

SCHEMBL3983585

CC#CC(CC(=O)OC)c1ccc(OCc2ccc(OC)cc2)cc1

nearest known ligand 0.82

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.82
GNA15 P30679 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL435839 0.90 FFAR1 (0.80) FFAR1GNA15
SCHEMBL17386171 0.90 FFAR1 (0.80) FFAR1GNA15
SCHEMBL3980603 0.90 FFAR1 (1.00) FFAR1GNA15
SCHEMBL3518855 0.90 FFAR1 (1.00) FFAR1GNA15
SCHEMBL3520994 0.90 FFAR1 (1.00) FFAR1GNA15
SCHEMBL13118039 0.90 FFAR1 (0.77) FFAR1GNA15
SCHEMBL13118284 0.84 FFAR1 (0.72) FFAR1GNA15
SCHEMBL19436258 0.82 FFAR1 (0.68) FFAR1GNA15
SCHEMBL13435422 0.82 FFAR1 (0.57) FFAR1GNA15
SCHEMBL19244288 0.81 FFAR1 (0.84) FFAR1GNA15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3443957-B1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CANCER LIMINAL BIOSCIENCES LTD (GB) 2020-11-25 EP disclosed
EP-3443957-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CANCER PROMETIC PHARMA SMT LIMITED (GB) 2019-02-20 EP disclosed
EP-2632452-B1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CANCER PROMETIC PHARMA SMT LTD (GB) 2018-09-26 EP disclosed
US-9439882-B2 Compounds and compositions for the treatment of cancer PROMETIC BIOSCIENCES INC. (CA) 2016-09-13 US disclosed
US-20150313856-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CANCER PROMETIC PHARMA SMT LIMITED (GB) 2015-11-05 US disclosed
US-9114118-B2 Compounds and compositions for the treatment of cancer PROMETIC BIOSCIENCES INC. (CA) 2015-08-25 US disclosed
EP-2632452-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CANCER ProMetic BioSciences Inc. (CA) 2013-09-04 EP disclosed
US-20130217645-A1 Compounds and Compositions for the Treatment of Cancer PROMETIC BIOSCIENCES INC. (CA) 2013-08-22 US disclosed
WO-2012097427-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CANCER PROMETIC BIOSCIENCES INC. (CA) 2012-07-26 WO disclosed
WO-2009055932-A1 SUBSTITUTED PHENYLPROPIONIC ACIDS AS STIMULATORS OF HEMATOPOIESIS AND ERYTHROPOIESIS PROMETIC BIOSCIENCES INC. (CA) 2009-05-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130217645-A1 Compounds and Compositions for the Treatment of Cancer DCK, TOP2B, TOP2A FFAR1 3574/4885GNA15 1866/4885
US-20150313856-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CANCER DCK, TOP2B, TOP2A FFAR1 3574/4885GNA15 1866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.