Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 14/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 4/20 | 0.47 |
| ▸ | CTSB | P07858 | 4/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.46 |
| ▸ | CTSH | P09668 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29866102 | 0.82 | PPARA (0.57) | CTSKATMAKT1CTSLCTSB | |
| SCHEMBL26932496 | 0.82 | PPARA (0.57) | CTSKATMAKT1CTSLCTSB | |
| SCHEMBL556571 | 0.82 | PPARA (0.57) | CTSKATMAKT1CTSLCTSB | |
| SCHEMBL390555 | 0.82 | ATM (0.62) | CTSKATMCTSLCTSBCTSS | |
| SCHEMBL1094506 | 0.82 | ATM (0.62) | CTSKATMCTSLCTSBCTSS | |
| SCHEMBL7094 | 0.82 | ATM (0.62) | CTSKATMCTSLCTSBCTSS | |
| SCHEMBL21910023 | 0.81 | SYK (0.56) | CTSKATMAKT1CTSLCTSB | |
| SCHEMBL30703902 | 0.81 | PSEN1 (0.54) | CTSKATMAKT1CTSLCTSB | |
| SCHEMBL555765 | 0.81 | CTSS (0.50) | CTSKATMAKT1CTSLCTSB | |
| SCHEMBL1457796 | 0.81 | CTSS (0.50) | CTSKATMAKT1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061460-A2 | 2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS | Albany Molecular Research, Inc. (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008019372-A2 | 2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS | ALBANY MOLECULAR RESEARCH, INC. (US) | 2008-02-14 | — | — | WO | disclosed |