Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.70 |
| ▸ | NPC1 | O15118 | 5/20 | 0.70 |
| ▸ | HTT | P42858 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.70 |
| ▸ | MITF | O75030 | 1/20 | 0.70 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | XBP1 | P17861 | 1/20 | 0.70 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | NPBWR1 | P48145 | 5/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1461789 | 0.82 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1HTTALDH1A1 | |
| SCHEMBL13967303 | 0.80 | NPBWR1 (0.58) | RAB9ASMN1; SMN2NPC1HTTALDH1A1 | |
| Pyrazon SCHEMBL1858918 | 0.79 | RAB9A (0.70) | RAB9ASMN1; SMN2NPC1HTTALDH1A1 | |
| Pyrazon SCHEMBL53824 | 0.79 | RAB9A (0.70) | RAB9ASMN1; SMN2NPC1HTTALDH1A1 | |
| SCHEMBL13219331 | 0.76 | RAB9A (0.64) | RAB9ASMN1; SMN2NPC1HTTALDH1A1 | |
| SCHEMBL4167058 | 0.76 | RAB9A (0.53) | RAB9ASMN1; SMN2NPC1HTTALDH1A1 | |
| Pyrazon SCHEMBL27859399 | 0.74 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1HTTALDH1A1 | |
| Pyrazon SCHEMBL16899678 | 0.74 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1HTTALDH1A1 | |
| SCHEMBL4172546 | 0.74 | SMN1; SMN2 (0.57) | RAB9ASMN1; SMN2NPC1HTTALDH1A1 | |
| SCHEMBL13942534 | 0.73 | NPC1 (0.70) | RAB9ASMN1; SMN2NPC1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413244-A2 | Process for separation and recycling of by-products from the wastewater of the synthesis of 5-amino-4-chloro-2-phenyl-3(2H)-pyridazinone | BASF Aktiengesellschaft (DE) | 1991-02-20 | — | — | EP | claimed |
| US-4454318-A | USING HYDROXY CONTAINING CATALYSTS | BASF AKTIENGESELLSCHAFT (DE) | 1984-06-12 | — | — | US | claimed |
| EP-0028359-B1 | METHOD FOR PRODUCING 4-CHLORO-5-AMINO-2-PHENYL-3(2H)-PYRIDAZINONE FROM 4,5-DICHLORO-2-PHENYL-3(2H)-PYRIDAZINONE AND AMMONIA | BASF Aktiengesellschaft (DE) | 1984-04-11 | — | — | EP | claimed |
| US-4286092-A | ACIDIFICATION OF AN ISOMERIC MIXTURE BY A MINERAL ACID TO DISSOLVE THE 4-AMINO ISOMER AND TO FORM A SUSPENSION | OXON ITALIA S.P.A. (IT) | 1981-08-25 | — | — | US | claimed |
| WO-1981001288-A1 | METHOD FOR PRODUCING 4-CHLORO-5-AMINO-2-PHENYL-3(2H)-PYRIDAZINONE FROM 4,5-DICHLORO-2-PHENYL-3(2H)-PYRIDAZINONE AND AMMONIA | KOEGE KEMISK VAERK (DK) | 1981-05-14 | — | — | WO | claimed |
| EP-0028359-A1 | Method for producing 4-chloro-5-amino-2-phenyl-3(2H)-pyridazinone from 4,5-dichloro-2-phenyl-3(2H)-pyridazinone and ammonia | BASF Aktiengesellschaft (DE) | 1981-05-13 | — | — | EP | claimed |
| US-4267323-A | DIAZOTIZATION AND CYCLIZATION OF 5-CHLORO-4-AMINO-2-PHENYL-3/2H/-PYRIDAZINONE; AGRICULTURE; DYEING; DRUGS | OXON ITALIA S.P.A. (IT) | 1981-05-12 | — | — | US | claimed |
| US-4237287-A | DIAZOTIZATION WITH SODIUM NITRITE AND CHLORINATION WITH THIONYL CHLORIDE | OXON ITALIA S.P.A. (IT) | 1980-12-02 | — | — | US | claimed |
| EP-1165520-B1 | METHOD FOR PRODUCING 4-AMINO-5-CHLORO-1-PHENYL PYRIDAZINONE | BASF SE (DE) | 2009-05-20 | — | — | EP | disclosed |
| US-20090012088-A1 | Compounds for the Treatment of Neurodegeneration and Stroke | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2009-01-08 | — | — | US | disclosed |
| US-20090012088-A1 | Compounds for the Treatment of Neurodegeneration and Stroke | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2009-01-08 | — | — | US | disclosed |
| US-20090012088-A1 | Compounds for the Treatment of Neurodegeneration and Stroke | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2009-01-08 | — | — | US | disclosed |
| US-20070032496-A1 | Compounds for the Treatment of Neurodegeneration and Stroke | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2007-02-08 | — | — | US | disclosed |
| US-20070032496-A1 | Compounds for the Treatment of Neurodegeneration and Stroke | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2007-02-08 | — | — | US | disclosed |
| US-4267323-A | DIAZOTIZATION AND CYCLIZATION OF 5-CHLORO-4-AMINO-2-PHENYL-3/2H/-PYRIDAZINONE; AGRICULTURE; DYEING; DRUGS | OXON ITALIA S.P.A. (IT) | 1981-05-12 | — | — | US | disclosed |
| EP-0026847-A1 | Process for preparing 4-amino-5-chloro-1-phenylpyridazone-(6) | BASF Aktiengesellschaft (DE) | 1981-04-15 | — | — | EP | disclosed |
| US-4237287-A | DIAZOTIZATION WITH SODIUM NITRITE AND CHLORINATION WITH THIONYL CHLORIDE | OXON ITALIA S.P.A. (IT) | 1980-12-02 | — | — | US | disclosed |
| US-4237287-A | DIAZOTIZATION WITH SODIUM NITRITE AND CHLORINATION WITH THIONYL CHLORIDE | OXON ITALIA S.P.A. (IT) | 1980-12-02 | — | — | US | disclosed |
| US-4237287-A | DIAZOTIZATION WITH SODIUM NITRITE AND CHLORINATION WITH THIONYL CHLORIDE | OXON ITALIA S.P.A. (IT) | 1980-12-02 | — | — | US | disclosed |
| US-3983168-A | HERBICIDES | MOBIL OIL CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032496-A1 | Compounds for the Treatment of Neurodegeneration and Stroke | PARP1, PARP12, PARP11 | RAB9A 2534/4885SMN1; SMN2 89/4885NPC1 996/4885 |
| US-20090012088-A1 | Compounds for the Treatment of Neurodegeneration and Stroke | PARP1, PARP12, PARP11 | RAB9A 2534/4885SMN1; SMN2 89/4885NPC1 996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.