Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4975666 | 0.85 | LMNA (0.35) | LMNAMC4RSMN1; SMN2ATM | |
| SCHEMBL10476537 | 0.85 | LMNA (0.35) | LMNAMC4RSMN1; SMN2ATM | |
| SCHEMBL12096020 | 0.73 | MEN1 (0.39) | — | |
| SCHEMBL3987567 | 0.71 | NPC1 (0.33) | LMNA | |
| SCHEMBL24278826 | 0.70 | MEN1 (0.41) | LMNAMC4RSMN1; SMN2 | |
| SCHEMBL28789407 | 0.70 | APOBEC3A (0.34) | LMNAMC4RSMN1; SMN2ATM | |
| SCHEMBL578810 | 0.70 | — | — | |
| SCHEMBL2936710 | 0.69 | CA1 (0.31) | — | |
| SCHEMBL933668 | 0.69 | CA1 (0.31) | — | |
| SCHEMBL8644323 | 0.69 | CA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562575-B1 | FUSED CYCLOALKYL AMIDES AND ACIDS AND THEIR THERAPEUTIC APPLICATIONS FOR THE TREATMENT OF I.A. EPILEPSY | ABBOTT LAB (US) | 2009-05-20 | — | — | EP | claimed |