Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2446696 | 0.95 | SNCA (0.69) | SNCAHIF1AALDH1A1CYP3A4CYP1A2 | |
| Iodide SCHEMBL9321342 | 0.95 | SNCA (0.69) | SNCAHIF1AALDH1A1CYP3A4CYP1A2 | |
| Bromide SCHEMBL163158 | 0.95 | SNCA (0.67) | SNCAHIF1AALDH1A1CYP1A2CYP2D6 | |
| Bromide SCHEMBL8331435 | 0.92 | SNCA (0.64) | SNCAHIF1AALDH1A1CYP3A4CYP1A2 | |
| Phosphine SCHEMBL27584733 | 0.92 | SNCA (0.64) | SNCAHIF1AALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL29918368 | 0.92 | SNCA (0.65) | SNCAHIF1AALDH1A1CYP1A2CYP2D6 | |
| Bromide SCHEMBL7728204 | 0.91 | SNCA (0.63) | SNCAHIF1AALDH1A1CYP3A4TSHR | |
| Bromide SCHEMBL2648850 | 0.90 | SNCA (0.62) | SNCAHIF1AALDH1A1CYP3A4CYP1A2 | |
| Bromide SCHEMBL28013112 | 0.90 | SNCA (0.62) | SNCAHIF1AALDH1A1CYP3A4CYP1A2 | |
| Bromide SCHEMBL28001010 | 0.90 | SNCA (0.62) | SNCAHIF1AALDH1A1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| US-5817430-A | POLYARYLENEVINYLENE POLYMER | XEROX CORPORATION (US) | 1998-10-06 | — | — | US | claimed |
| US-5753757-A | Electroluminescent polymer compositions and processes thereof | XEROX CORPORATION (US) | 1998-05-19 | — | — | US | claimed |
| US-5709976-A | Coated papers | XEROX CORPORATION (US) | 1998-01-20 | — | — | US | claimed |
| EP-0615853-B1 | Recording sheets containing phosphonium compounds | XEROX CORP (US) | 1996-10-16 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| CN-114496571-A | Method for producing electrolytic capacitor | 钰邦科技股份有限公司 | 2022-05-13 | — | — | CN | disclosed |
| US-10928728-B2 | Photoactivable nitrogen bases | BASF SE (DE) | 2021-02-23 | — | — | US | disclosed |
| US-20210033972-A1 | PHOTOACTIVABLE NITROGEN BASES | BASF SE (DE) | 2021-02-04 | — | — | US | disclosed |
| US-20180217498-A1 | PHOTOACTIVABLE NITROGEN BASES | BASF SE (DE) | 2018-08-02 | — | — | US | disclosed |
| US-9921477-B2 | Photoactivable nitrogen bases | BASE SE (DE) | 2018-03-20 | — | — | US | disclosed |
| US-9142782-B2 | Organic light-emitting material, device and method | CAMBRIDGE DISPLAY TECHNOLOGY, LTD. (GB) | 2015-09-22 | — | — | US | disclosed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | disclosed |
| EP-0615853-A1 | Recording sheets containing phosphonium compounds | XEROX CORPORATION (US) | 1994-09-21 | — | — | EP | disclosed |
| EP-0610283-A1 | DNA BIS-INTERCALATORS | ISIS INNOVATION LIMITED (GB) | 1994-08-17 | — | — | EP | disclosed |
| US-5328961-A | Electrically conductive polythiophenecarbonyl polymer networks | FORD MOTOR COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5274046-A | Electrically conductive polypyrrolecarbonyl polymer networks | FORD MOTOR COMPANY (US) | 1993-12-28 | — | — | US | disclosed |
| WO-1993008165-A1 | DNA BIS-INTERCALATORS | ISIS INNOVATION LIMITED (GB) | 1993-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210033972-A1 | PHOTOACTIVABLE NITROGEN BASES | CBR1, ARNT, NR0B1 | SNCA 2054/4885HIF1A 1258/4885ALDH1A1 1659/4885 |
| US-10928728-B2 | Photoactivable nitrogen bases | CBR1, NR0B1, NR0B2 | SNCA 1887/4885HIF1A 1136/4885ALDH1A1 1733/4885 |
| US-20180217498-A1 | PHOTOACTIVABLE NITROGEN BASES | CBR1, NR0B1, NR0B2 | SNCA 1887/4885HIF1A 1136/4885ALDH1A1 1733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.