Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 15/20 | 0.48 |
| ▸ | BCL2 | P10415 | 11/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 10/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971345 | 0.80 | KMT2A (0.55) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL8640471 | 0.76 | ALDH1A1 (0.51) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL4263829 | 0.75 | BCL2L1 (0.57) | BCL2L1BCL2MCL1BAK1 | |
| SCHEMBL1113832 | 0.74 | BCL2L1 (0.64) | BCL2L1BCL2MCL1MAPTALDH1A1 | |
| SCHEMBL20429302 | 0.73 | BCL2L1 (0.50) | MEN1KMT2ABCL2L1BCL2MCL1 | |
| SCHEMBL4273569 | 0.70 | BCL2L1 (0.54) | MEN1KMT2ABCL2L1BCL2MCL1 | |
| SCHEMBL13754458 | 0.70 | BCL2L1 (0.49) | MEN1KMT2ABCL2L1BCL2MCL1 | |
| SCHEMBL27604839 | 0.69 | KMT2A (0.52) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL13754543 | 0.69 | BCL2L1 (0.53) | BCL2L1BCL2MCL1BAK1 | |
| SCHEMBL10222787 | 0.69 | BCL2L1 (0.58) | BCL2L1BCL2MCL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067697-A1 | THERAPEUTIC COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2009-05-28 | — | — | WO | claimed |
| WO-2009067697-A1 | THERAPEUTIC COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2009-05-28 | — | — | WO | disclosed |