Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27604839 | 0.89 | KMT2A (0.52) | KMT2APKMMAPTNPC1RAB9A | |
| SCHEMBL103245 | 0.82 | KMT2A (0.63) | KMT2APKMMAPTNPC1RAB9A | |
| SCHEMBL3984840 | 0.80 | MEN1 (0.49) | KMT2AMAPTNPC1RAB9AMEN1 | |
| SCHEMBL8640471 | 0.80 | ALDH1A1 (0.51) | KMT2APKMMAPTRAB9AMEN1 | |
| SCHEMBL18184326 | 0.75 | KMT2A (0.65) | KMT2APKMMAPTNPC1RAB9A | |
| SCHEMBL8150179 | 0.75 | MAPT (0.58) | KMT2APKMMAPTNPC1RAB9A | |
| SCHEMBL709343 | 0.75 | KMT2A (0.65) | KMT2APKMMAPTNPC1RAB9A | |
| SCHEMBL6995037 | 0.75 | L3MBTL1 (0.44) | KMT2APKMMAPTNPC1RAB9A | |
| SCHEMBL2675694 | 0.74 | MAPT (0.54) | KMT2AMAPTMEN1RECQLHTT | |
| SCHEMBL12290345 | 0.73 | MAPT (0.64) | KMT2APKMMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |