Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3984196 | 0.81 | MAPT (0.41) | ALDH1A1SMN1; SMN2MAPK1POLBNPSR1 | |
| SCHEMBL4303747 | 0.75 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2POLBPABPC1APOBEC3A | |
| SCHEMBL5494773 | 0.74 | KDM4E (0.45) | ALDH1A1SMN1; SMN2MAPK1POLBGAA | |
| SCHEMBL6579486 | 0.72 | NCEH1 (0.55) | PTGDR2ALDH1A1SMN1; SMN2POLBPABPC1 | |
| SCHEMBL11608387 | 0.71 | KDM4E (0.42) | ALDH1A1SMN1; SMN2MAPK1POLBGAA | |
| SCHEMBL16559854 | 0.70 | ALDH1A1 (0.55) | PTGDR2ALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL20074382 | 0.70 | POLB (0.49) | PTGDR2ALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL4517104 | 0.69 | MEN1 (0.57) | PTGDR2ALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL1404080 | 0.69 | KDM4E (0.54) | PTGDR2ALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL29119726 | 0.69 | NPC1 (0.37) | ALDH1A1SMN1; SMN2MAPK1POLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060209-A1 | 6,6-FUSED BICYCLIC AROMATIC COMPOUNDS AND THEIR THERAPEUTI USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |