Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.57 |
| ▸ | NPC1 | O15118 | 12/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13845742 | 0.83 | NPC1 (0.50) | RAB9ANPC1SMN1; SMN2KMT2ATP53 | |
| SCHEMBL13845732 | 0.81 | RPS6KA3 (0.49) | RAB9ANPC1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL14072168 | 0.80 | RPS6KA3 (0.48) | RAB9ANPC1KMT2AHPGDRPS6KA3 | |
| SCHEMBL13845779 | 0.76 | RPS6KA3 (0.48) | RAB9ANPC1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL14072191 | 0.76 | RPS6KA3 (0.47) | RAB9ANPC1SMN1; SMN2KMT2ARPS6KA3 | |
| SCHEMBL10143997 | 0.76 | SMN1; SMN2 (0.53) | RAB9ANPC1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL13879891 | 0.76 | RPS6KA3 (0.45) | KMT2AHPGDRPS6KA3POLBKDM4E | |
| SCHEMBL14543365 | 0.75 | RPS6KA3 (0.51) | RAB9ANPC1SMN1; SMN2HPGDRPS6KA3 | |
| SCHEMBL13845690 | 0.74 | RPS6KA3 (0.50) | RAB9ANPC1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL13879895 | 0.74 | RPS6KA3 (0.46) | RAB9ANPC1SMN1; SMN2KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060215-A1 | POLYAMIDES | SPIROGEN LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |