Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4274506 | 0.85 | KIT (0.43) | ALDH1A1NPC1RAB9AKDM4EHTT | |
| SCHEMBL10143997 | 0.80 | SMN1; SMN2 (0.53) | RPS6KA3ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL14072168 | 0.79 | RPS6KA3 (0.48) | RPS6KA3ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL13845690 | 0.78 | RPS6KA3 (0.50) | RPS6KA3ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL3985808 | 0.76 | RAB9A (0.57) | RPS6KA3ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL14072191 | 0.75 | RPS6KA3 (0.47) | RPS6KA3ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL14543365 | 0.74 | RPS6KA3 (0.51) | RPS6KA3ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23745118 | 0.74 | RPS6KA3 (0.43) | RPS6KA3NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL108857 | 0.73 | BRD4 (0.63) | BRD4KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13845752 | 0.73 | RPS6KA3 (0.46) | RPS6KA3ALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060215-A1 | POLYAMIDES | SPIROGEN LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |