Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MMP8 | P22894 | 2/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3989405 | 0.90 | LOXL2 (0.30) | — | |
| SCHEMBL13796752 | 0.89 | SLC7A5 (0.32) | — | |
| SCHEMBL13795944 | 0.89 | SLC7A5 (0.32) | — | |
| SCHEMBL13796424 | 0.88 | SLC7A5 (0.32) | — | |
| SCHEMBL13796798 | 0.86 | SLC1A1 (0.34) | — | |
| SCHEMBL3994987 | 0.85 | KLKB1 (0.32) | — | |
| SCHEMBL13796723 | 0.85 | MC4R (0.34) | — | |
| SCHEMBL13795593 | 0.84 | POLB (0.33) | — | |
| SCHEMBL13796824 | 0.83 | NR1I2 (0.31) | — | |
| SCHEMBL3993021 | 0.79 | TRPA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | disclosed |