Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL333232 | 0.73 | KDM4E (0.52) | — | |
| SCHEMBL9465582 | 0.69 | KMO (0.33) | — | |
| SCHEMBL9465723 | 0.66 | AOC3 (0.32) | — | |
| SCHEMBL6327318 | 0.65 | HDAC8 (0.41) | CLK4ADRB2 | |
| SCHEMBL18729418 | 0.64 | NISCH (0.42) | — | |
| SCHEMBL9466191 | 0.64 | LTA4H (0.37) | — | |
| SCHEMBL171853 | 0.64 | HDAC8 (0.47) | CLK4ADRB2 | |
| SCHEMBL1435891 | 0.63 | CYP2A6 (0.54) | — | |
| SCHEMBL4270187 | 0.61 | HDAC8 (0.44) | CLK4ADRB2 | |
| Hydrochloric Acid SCHEMBL6534749 | 0.61 | HDAC8 (0.44) | CLK4ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2034993-A2 | PYRAZINONES AS CELLULAR PROLIFERATION INHIBITORS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007149448-A2 | PYRAZINONES AS CELLULAR PROLIFERATION INHIBITORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-12-27 | — | — | WO | disclosed |