Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14783801 | 0.85 | KDM4E (0.44) | KDM4EALDH1A1USP2HPGDHIF1A | |
| SCHEMBL3649084 | 0.81 | MAPT (0.40) | KDM4EALDH1A1USP2HPGDHIF1A | |
| SCHEMBL31432707 | 0.79 | LMNA (0.39) | KDM4EALDH1A1USP2HPGDHIF1A | |
| SCHEMBL27901280 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1USP2HPGDHIF1A | |
| SCHEMBL31432595 | 0.78 | EPAS1 (0.40) | KDM4EALDH1A1USP2HPGDHIF1A | |
| SCHEMBL19877832 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1USP2HPGDHIF1A | |
| SCHEMBL4404567 | 0.78 | NPC1 (0.42) | KDM4EALDH1A1USP2HPGDHIF1A | |
| SCHEMBL1462237 | 0.78 | TRPV4 (0.39) | KDM4EALDH1A1HPGDADORA1ADORA2A | |
| SCHEMBL15846053 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1USP2HPGDHIF1A | |
| SCHEMBL186647 | 0.77 | MAPT (0.43) | KDM4EALDH1A1USP2HPGDHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060209-A1 | 6,6-FUSED BICYCLIC AROMATIC COMPOUNDS AND THEIR THERAPEUTI USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |