Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.43 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398665 | 1.00 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2AKR1C3POLBKEAP1 | |
| SCHEMBL398542 | 0.86 | AKR1C3 (0.50) | ALDH1A1SMN1; SMN2AKR1C3HPGDTBXAS1 | |
| SCHEMBL398543 | 0.86 | AKR1C3 (0.50) | ALDH1A1SMN1; SMN2AKR1C3HPGDTBXAS1 | |
| SCHEMBL396886 | 0.85 | HDAC1 (0.60) | ALDH1A1AKR1C3KEAP1HPGDHDAC3 | |
| SCHEMBL396885 | 0.85 | HDAC1 (0.60) | ALDH1A1AKR1C3KEAP1HPGDHDAC3 | |
| SCHEMBL397627 | 0.81 | AKR1C3 (0.55) | ALDH1A1SMN1; SMN2AKR1C3KEAP1PGR | |
| SCHEMBL397626 | 0.81 | AKR1C3 (0.55) | ALDH1A1SMN1; SMN2AKR1C3KEAP1PGR | |
| SCHEMBL396992 | 0.81 | HDAC1 (0.62) | ALDH1A1SMN1; SMN2POLBHPGDHDAC3 | |
| SCHEMBL396991 | 0.81 | HDAC1 (0.62) | ALDH1A1SMN1; SMN2POLBHPGDHDAC3 | |
| SCHEMBL396989 | 0.79 | HDAC1 (0.60) | ALDH1A1AKR1C3POLBKEAP1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101332-B2 | Negative-working lithographic printing plate precursor and method of lithographic printing using same | FUJIFILM CORPORATION (JP) | 2012-01-24 | — | — | US | disclosed |
| US-20090246688-A1 | NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME | FUJIFILM CORPORATION (JP) | 2009-10-01 | — | — | US | disclosed |