Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397627 | 1.00 | AKR1C3 (0.55) | AKR1C3HDAC1KEAP1PTGS2ESR1 | |
| SCHEMBL398076 | 0.84 | HPGD (0.57) | AKR1C3HDAC1PTGS2HPGDKDM4E | |
| SCHEMBL398077 | 0.84 | HPGD (0.57) | AKR1C3HDAC1PTGS2HPGDKDM4E | |
| SCHEMBL398665 | 0.81 | ALDH1A1 (0.55) | AKR1C3HDAC1KEAP1HPGDALDH1A1 | |
| SCHEMBL397675 | 0.81 | HDAC1 (0.78) | AKR1C3HDAC1KEAP1ALDH1A1HDAC3 | |
| SCHEMBL398664 | 0.81 | ALDH1A1 (0.55) | AKR1C3HDAC1KEAP1HPGDALDH1A1 | |
| SCHEMBL397674 | 0.81 | HDAC1 (0.78) | AKR1C3HDAC1KEAP1ALDH1A1HDAC3 | |
| SCHEMBL2462984 | 0.80 | AKR1C3 (0.82) | AKR1C3KDM4EALDH1A1HTTTBXAS1 | |
| SCHEMBL2462983 | 0.80 | AKR1C3 (0.82) | AKR1C3KDM4EALDH1A1HTTTBXAS1 | |
| SCHEMBL397356 | 0.79 | HDAC1 (0.62) | HDAC1HPGDALDH1A1LMNAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101332-B2 | Negative-working lithographic printing plate precursor and method of lithographic printing using same | FUJIFILM CORPORATION (JP) | 2012-01-24 | — | — | US | disclosed |
| EP-1972440-B1 | Negative lithographic printing plate precursor and lithographic printing method using the same | FUJIFILM CORP (JP) | 2010-06-23 | — | — | EP | disclosed |
| US-20090246688-A1 | NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME | FUJIFILM CORPORATION (JP) | 2009-10-01 | — | — | US | disclosed |
| EP-2105298-A1 | Negative-working lithographic printing plate precursor and method of lithographic printing using same | Fujifilm Corporation (JP) | 2009-09-30 | — | — | EP | disclosed |
| US-20080233516-A1 | NEGATIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD USING THE SAME | FUJIFILM CORPORATION (JP) | 2008-09-25 | — | — | US | disclosed |
| EP-1972440-A2 | Negative lithographic printing plate precursor and lithographic printing method using the same | FUJIFILM Corporation (JP) | 2008-09-24 | — | — | EP | disclosed |