Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 14/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.52 |
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315806 | 1.00 | KDM4C (0.59) | KDM4CFFAR1PPARDPPARGPPARA | |
| SCHEMBL12510404 | 0.83 | KDM4C (0.53) | KDM4C | |
| SCHEMBL14299176 | 0.83 | HTR6 (0.57) | KDM4C | |
| SCHEMBL10110774 | 0.83 | KDM4C (0.53) | KDM4C | |
| SCHEMBL10110778 | 0.82 | KDM4C (0.62) | KDM4C | |
| SCHEMBL30301824 | 0.79 | FFAR1 (0.52) | KDM4CFFAR1PPARD | |
| SCHEMBL3590904 | 0.79 | FFAR1 (0.52) | KDM4CFFAR1PPARD | |
| SCHEMBL315960 | 0.78 | KDM4C (0.48) | KDM4C | |
| SCHEMBL315961 | 0.78 | KDM4C (0.48) | KDM4C | |
| SCHEMBL316157 | 0.78 | KDM4C (0.48) | KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035370-A2 | TETRALIN AND INDANE DERIVATIVES AND USES THEREOF | F. Hoffmann-Roche AG (CH) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007147771-A2 | TETRALIN AND INDANE DERIVATIVES AND USES THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2007-12-27 | — | — | WO | disclosed |