Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3648327 | 0.80 | EPHX2 (0.38) | — | |
| SCHEMBL3936735 | 0.77 | EPHX1 (0.38) | ALDH1A1SMN1; SMN2ATMPOLBLMNA | |
| SCHEMBL3989590 | 0.73 | EPHX1 (0.37) | ALDH1A1SMN1; SMN2ATMPOLBLMNA | |
| SCHEMBL31278392 | 0.71 | FFAR3 (0.35) | — | |
| SCHEMBL147119 | 0.70 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2ATMGAAL3MBTL1 | |
| SCHEMBL919280 | 0.70 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2ATMGAAL3MBTL1 | |
| SCHEMBL147120 | 0.70 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2ATMGAAL3MBTL1 | |
| Acetic Acid SCHEMBL7704610 | 0.70 | ATM (0.47) | ALDH1A1SMN1; SMN2ATMLMNAGAA | |
| SCHEMBL38557 | 0.68 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2ATMLMNAGAA | |
| SCHEMBL1468176 | 0.68 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2ATMLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067547-A1 | POLO-LIKE KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-05-28 | — | — | WO | disclosed |