Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 13/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.36 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3986499 | 0.88 | PTPRB (0.40) | PTPRBHTTHSPA5HSPA9HSPA2 | |
| SCHEMBL3995096 | 0.87 | PTPRB (0.40) | PTPRBCA2CTSSCTSK | |
| SCHEMBL3995019 | 0.84 | PTPRB (0.38) | PTPRBHSPA5 | |
| SCHEMBL3993082 | 0.84 | PTPRB (0.40) | PTPRBHSPA5HSPA9HSPA2 | |
| SCHEMBL3995134 | 0.80 | ALOX12 (0.39) | PTPRB | |
| SCHEMBL13796750 | 0.80 | PTPRB (0.36) | PTPRBHTTHSPA5HSPA9HSPA2 | |
| SCHEMBL3988530 | 0.80 | PTPRB (0.36) | PTPRBHTTHSPA5HSPA9HSPA2 | |
| SCHEMBL3988336 | 0.78 | PTPRB (0.46) | PTPRBCTSSCTSK | |
| SCHEMBL19257971 | 0.74 | PTPRB (0.49) | PTPRBALDH1A1HPGDHTT | |
| SCHEMBL10411484 | 0.74 | PTPRB (0.55) | PTPRBALDH1A1HPGDHTTCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | disclosed |