Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 3/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 5/20 | 0.36 |
| ▸ | HSPA9 | P38646 | 3/20 | 0.36 |
| ▸ | HSPA2 | P54652 | 2/20 | 0.36 |
| ▸ | MRE11 | P49959 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3987138 | 0.88 | PTPRB (0.49) | PTPRBHSPA5HSPA9HSPA2HTT | |
| SCHEMBL3993082 | 0.88 | PTPRB (0.40) | PTPRBCCR3ADRB3HSPA5HSPA9 | |
| SCHEMBL3995134 | 0.83 | ALOX12 (0.39) | PTPRBCCR3ADRB3MRE11ALOX15 | |
| SCHEMBL13796750 | 0.83 | PTPRB (0.36) | PTPRBCCR3ADRB3HSPA5HSPA9 | |
| SCHEMBL3988530 | 0.83 | PTPRB (0.36) | PTPRBCCR3ADRB3HSPA5HSPA9 | |
| SCHEMBL3995019 | 0.81 | PTPRB (0.38) | PTPRBCCR3ADRB3HSPA5MRE11 | |
| SCHEMBL3995096 | 0.80 | PTPRB (0.40) | PTPRBADRB3 | |
| SCHEMBL4657375 | 0.79 | ACACB (0.38) | ALOX15ALOX12LMNATP53HTT | |
| SCHEMBL3988336 | 0.78 | PTPRB (0.46) | PTPRBCCR3ADRB3 | |
| SCHEMBL3987548 | 0.77 | ERCC1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | disclosed |