Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phenylalanine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.81 |
| ▸ | ALPI | P09923 | 1/20 | 0.81 |
| ▸ | PKM | P14618 | 1/20 | 0.81 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.81 |
| ▸ | XIAP | P98170 | 1/20 | 0.81 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.64 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.64 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.64 |
| ▸ | CPA1 | P15085 | 2/20 | 0.59 |
| ▸ | CPB1 | P15086 | 1/20 | 0.59 |
| ▸ | CPA3 | P15088 | 1/20 | 0.59 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.59 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.51 |
| ▸ | TPH1 | P17752 | 1/20 | 0.50 |
| ▸ | GRB2 | P62993 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine SCHEMBL27548157 | 1.00 | SLC7A5 (0.81) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL27864433 | 1.00 | SLC7A5 (0.81) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL7248684 | 1.00 | SLC7A5 (0.81) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL1897792 | 1.00 | SLC7A5 (0.81) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL13835334 | 0.98 | SLC7A5 (0.79) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL29211050 | 0.95 | SLC7A5 (0.73) | SLC7A5ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL22556045 | 0.95 | SLC7A5 (0.73) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL13836013 | 0.95 | SLC7A5 (0.73) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL630407 | 0.95 | SLC7A5 (0.73) | SLC7A5ALPIPKMPTGS1XIAP | |
| Phenylalanine SCHEMBL3360080 | 0.93 | SLC7A5 (0.71) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117054657-B | Combined blocking agent and application thereof in latex immunoturbidimetry detection | 北京豪迈生物工程股份有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117388421-A | Method for identifying forage grass rhizosphere secretion and differential metabolite thereof based on non-targeted metabonomics | 中国农业大学 | 2024-01-12 | — | — | CN | claimed |
| CN-117054657-A | Combined blocking agent and application thereof in latex immunoturbidimetry detection | 北京豪迈生物工程股份有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-112725803-B | Titanium etching solution for wafer level packaging | 江苏奥首材料科技有限公司 | 2022-11-15 | — | — | CN | claimed |
| CN-108267580-B | Immunoturbidimetric reagent for inhibiting IgM type RF interference by using active group of specific dipeptide | 南京天纵易康生物科技股份有限公司 | 2021-05-25 | — | — | CN | claimed |
| CN-112725803-A | Titanium etching solution for wafer level packaging | 江苏奥首材料科技有限公司 | 2021-04-30 | — | — | CN | claimed |
| CN-110357942-A | A kind of two peptide combinations and the application in terms of enhancing CIK cell activity | 南京乐扬医药科技有限公司 | 2019-10-22 | — | — | CN | claimed |
| CN-108267580-A | A kind of active group using specific dipeptides inhibits the immunoturbidimetry reagent of IgM types RF interference | 南京天纵易康生物科技股份有限公司 | 2018-07-10 | — | — | CN | claimed |
| CN-104083778-B | Paramagnetic metal complex that aspartic acid-phenylalanine copolymer is modified and its preparation method and application | 中国科学院长春应用化学研究所 | 2017-01-04 | — | — | CN | claimed |
| US-4394308-A | Method of producing α-L-aspartyl-L-phenylalanine methylesters | CHIMICASA GMBH (CH) | 1983-07-19 | — | — | US | claimed |
| CN-117054657-B | Combined blocking agent and application thereof in latex immunoturbidimetry detection | 北京豪迈生物工程股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-117740961-A | Compound analysis method of liquorice and liquorice probiotics fermentation preparation | 北京中医药大学 | 2024-03-22 | — | — | CN | disclosed |
| US-11884718-B2 | Potent zika virus-specific and cross-neutralizing monoclonal antibodies to zika and dengue viruses following ZIKV infection or vaccination | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) | 2024-01-30 | — | — | US | disclosed |
| CN-117388421-A | Method for identifying forage grass rhizosphere secretion and differential metabolite thereof based on non-targeted metabonomics | 中国农业大学 | 2024-01-12 | — | — | CN | disclosed |
| CN-117054657-A | Combined blocking agent and application thereof in latex immunoturbidimetry detection | 北京豪迈生物工程股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| EP-0170148-A2 | Process for the preparation of alfa-L-aspartyl-L-phenylalanine alkyl esters | FARCHEMIA S.p.A. (IT) | 1986-02-05 | — | — | EP | disclosed |
| EP-0169937-A2 | Process for the preparation of alpha-L-aspartyl-L-phenylalanine alkyl esters | FARCHEMIA S.p.A. (IT) | 1986-02-05 | — | — | EP | disclosed |
| US-4394308-A | Method of producing α-L-aspartyl-L-phenylalanine methylesters | CHIMICASA GMBH (CH) | 1983-07-19 | — | — | US | disclosed |
| US-4233439-A | ARTIFICAL SWEETNER; SUITABLE FOR DIABETICS | SUDDEUTSCHE ZUCKER-AKTIENGESELLSCHAFT (DE) | 1980-11-11 | — | — | US | disclosed |
| US-4117173-A | USE OF GLUCOPYRANOSIDO-1,6-MANNITOL AS A SUGAR SUBSTITUTE | SUDDEUTSCHE ZUCKER-AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |