Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL268363 | 1.00 | LMNA (0.47) | LMNANSD2KMT2AMAPK8ATM | |
| SCHEMBL270028 | 0.90 | RAB9A (0.52) | LMNAKMT2AEGLN1ALDH1A1MEN1 | |
| SCHEMBL270246 | 0.90 | HPGD (0.51) | LMNAKMT2AMAPK8GAAHPGD | |
| Hydrochloric Acid SCHEMBL269795 | 0.89 | RAB9A (0.51) | LMNAKMT2AEGLN1ALDH1A1MEN1 | |
| SCHEMBL268272 | 0.88 | LMNA (0.48) | LMNAKMT2AMAPK8HPGDL3MBTL1 | |
| SCHEMBL268900 | 0.88 | KMT2A (0.53) | LMNAKMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL268989 | 0.88 | LMNA (0.45) | LMNAKMT2AMAPK8GAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL270565 | 0.87 | LMNA (0.47) | LMNAKMT2AMAPK8HPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL270684 | 0.87 | LMNA (0.44) | LMNAKMT2AMAPK8GAAL3MBTL1 | |
| SCHEMBL268886 | 0.86 | NPC1 (0.42) | LMNAKMT2AMAPK8ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912946-B1 | PYRIDINE DERIVATIVES AS DIPEPTEDYL PEPTIDASE INHIBITORS | LILLY CO ELI (US) | 2009-05-27 | — | — | EP | disclosed |