Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CD38 | P28907 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28947822 | 0.85 | MAOB (0.52) | ALDH1A1MAPTMEN1HPGDMAPK1 | |
| SCHEMBL322590 | 0.82 | PDE4A (0.52) | ALDH1A1MAPTKDM4EMEN1NPC1 | |
| SCHEMBL28467263 | 0.82 | PDE4A (0.52) | ALDH1A1MAPTKDM4EMEN1NPC1 | |
| SCHEMBL27619310 | 0.81 | ALOX5 (0.57) | ALDH1A1MAPTTUBB1KDM4EMEN1 | |
| SCHEMBL13846509 | 0.81 | MAPT (0.49) | ALDH1A1AOX1MAPTTUBB4ATUBB | |
| SCHEMBL5329103 | 0.79 | PDGFRB (0.47) | ALDH1A1MAPTKDM4ENPC1HPGD | |
| SCHEMBL11289190 | 0.79 | MAOB (0.57) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28764944 | 0.78 | CYP17A1 (0.54) | ALDH1A1MAPTTUBB1KDM4EMEN1 | |
| SCHEMBL695680 | 0.78 | CYP17A1 (0.54) | ALDH1A1MAPTTUBB1KDM4EMEN1 | |
| SCHEMBL498309 | 0.76 | APP (0.67) | HSD17B10CYP3A4ALOX15APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067697-A1 | THERAPEUTIC COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2009-05-28 | — | — | WO | claimed |
| WO-2009067697-A1 | THERAPEUTIC COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2009-05-28 | — | — | WO | disclosed |