Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27619310 | 0.84 | ALOX5 (0.57) | MAPTMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL8338706 | 0.84 | FYN (0.61) | MAPTMEN1MAPK1KMT2ALMNA | |
| SCHEMBL218637 | 0.83 | ACHE (0.62) | MAPTMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL29398758 | 0.83 | ACHE (0.62) | MAPTMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL11289190 | 0.82 | MAOB (0.57) | MAPTMEN1MAPK1KMT2ALMNA | |
| SCHEMBL12333997 | 0.81 | ACHE (0.67) | MAPTMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL1047750 | 0.81 | ACHE (0.67) | MAPTMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL31042563 | 0.81 | ACHE (0.67) | MAPTMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL3987934 | 0.81 | ALDH1A1 (0.44) | MAPTMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL8338270 | 0.79 | ACHE (0.52) | MAPTTDP1RORCACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067697-A1 | THERAPEUTIC COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2009-05-28 | — | — | WO | disclosed |