SCHEMBL3988047

SCHEMBL3988047

C=C(C)C(=O)OCCOCC(CCCCCCCCCC)CCCCCCCCCCCC

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.61
THRB P10828 1/20 0.54
PLA2G2C Q5R387 6/20 0.41
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
DGKA P23743 1/20 0.38
MMP9 P14780 1/20 0.37
MMP8 P22894 1/20 0.37
MMP14 P50281 1/20 0.37
ZDHHC7 Q9NXF8 1/20 0.37
LMNA P02545 1/20 0.37
CES2 O00748 1/20 0.37
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6829351 1.00 TSHR (0.61) TSHRTHRBPLA2G2CPRSS1PRSS2
SCHEMBL4570718 1.00 TSHR (0.61) TSHRTHRBPLA2G2CPRSS1PRSS2
SCHEMBL10049282 0.99 TSHR (0.59) TSHRTHRBPLA2G2CPRSS1PRSS2
SCHEMBL1982685 0.88 THRB (0.54) TSHRTHRBPLA2G2CPRSS1PRSS2
SCHEMBL26920606 0.87 THRB (0.53) TSHRTHRBPLA2G2CPRSS1PRSS2
SCHEMBL22435238 0.87 TSHR (0.59) TSHRTHRBPLA2G2CCYP3A4
SCHEMBL985292 0.87 THRB (0.53) TSHRTHRBPLA2G2CPRSS1PRSS2
SCHEMBL21853803 0.86 TSHR (0.61) TSHRTHRBPRSS1PRSS2PRSS3
SCHEMBL17941650 0.86 TSHR (0.61) TSHRTHRBPRSS1PRSS2PRSS3
SCHEMBL21853810 0.86 TSHR (0.61) TSHRTHRBPRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170088789-A1 LUBRICANTS CONTAINING BLENDS OF POLYMERS THE LUBRIZOL CORPORATION 2017-03-30 US disclosed
EP-3119860-A1 LUBRICANTS CONTAINING BLENDS OF POLYMERS The Lubrizol Corporation (US) 2017-01-25 EP disclosed
WO-2015142482-A1 LUBRICANTS CONTAINING BLENDS OF POLYMERS THE LUBRIZOL CORPORATION (US) 2015-09-24 WO disclosed
US-20130005628-A1 Novel Polymers and Methods of Controlling Viscosity THE LUBRIZOL CORPORATION (US) 2013-01-03 US disclosed
US-8343900-B2 Polymers and methods of controlling viscosity THE LUBRIZOL CORPORATION (US) 2013-01-01 US disclosed
US-8293689-B2 Lubricating composition containing a polymer and antiwear agents THE LUBRIZOL CORPORATION (US) 2012-10-23 US disclosed
US-20090312210-A1 Lubricating Composition Containing a Polymer and Antiwear Agents THE LUBRIZOL CORPORATION (US) 2009-12-17 US disclosed
US-20090221461-A1 Novel Polymers and Methods of Controlling Viscosity THE LUBRIZOL CORPORATION (US) 2009-09-03 US disclosed
EP-2029707-A2 LUBRICATING COMPOSITION CONTAINING A POLYMER AND ANTIWEAR AGENTS The Lubrizol Corporation (US) 2009-03-04 EP disclosed
WO-2007133995-A2 LUBRICATING COMPOSITION CONTAINING A POLYMER AND ANTIWEAR AGENTS THE LUBRIZOL CORPORATION (US) 2007-11-22 WO disclosed
US-6746993-B2 POLYMER CONTAINING C1-40ALKYL GROUP-CONTAINING (METH) ACRYLATES, (B) ALKYL ALKENYL ETHERS, (C) ALKENYL CARBOXYLATES, AND A NITROGEN CONTAINING UNSATURATED MONOMERS SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2004-06-08 US disclosed
US-20040077509-A1 Viscosity index improver and lube oil containing the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2004-04-22 US disclosed
US-20030104955-A1 Viscosity index improver and lube oil containing the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2003-06-05 US disclosed