Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | PLA2G2C | Q5R387 | 6/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829351 | 1.00 | TSHR (0.61) | TSHRTHRBPLA2G2CPRSS1PRSS2 | |
| SCHEMBL3988047 | 1.00 | TSHR (0.61) | TSHRTHRBPLA2G2CPRSS1PRSS2 | |
| SCHEMBL10049282 | 0.99 | TSHR (0.59) | TSHRTHRBPLA2G2CPRSS1PRSS2 | |
| SCHEMBL1982685 | 0.88 | THRB (0.54) | TSHRTHRBPLA2G2CPRSS1PRSS2 | |
| SCHEMBL26920606 | 0.87 | THRB (0.53) | TSHRTHRBPLA2G2CPRSS1PRSS2 | |
| SCHEMBL22435238 | 0.87 | TSHR (0.59) | TSHRTHRBPLA2G2CCYP3A4 | |
| SCHEMBL985292 | 0.87 | THRB (0.53) | TSHRTHRBPLA2G2CPRSS1PRSS2 | |
| SCHEMBL21853803 | 0.86 | TSHR (0.61) | TSHRTHRBPRSS1PRSS2PRSS3 | |
| SCHEMBL17941650 | 0.86 | TSHR (0.61) | TSHRTHRBPRSS1PRSS2PRSS3 | |
| SCHEMBL21853810 | 0.86 | TSHR (0.61) | TSHRTHRBPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8505631-B2 | Compositions having HASE rheology modifiers | RHODIA OPERATIONS (FR) | 2013-08-13 | — | — | US | disclosed |
| US-8501983-B2 | Composition having HASE rheology modifiers | RHODIA OPERATIONS (FR) | 2013-08-06 | — | — | US | disclosed |
| US-8501860-B2 | Compositions having HASE rheology modifiers | RHODIA OPERATIONS (FR) | 2013-08-06 | — | — | US | disclosed |
| US-20120123149-A1 | Composition having hase rheology modifiers | RHODIA OPERATIONS (FR) | 2012-05-17 | — | — | US | disclosed |
| US-20120121523-A1 | Compositions having hase rheology modifiers | RHODIA OPERATIONS (FR) | 2012-05-17 | — | — | US | disclosed |
| US-20120116005-A1 | Compositions having hase rheology modifiers | RHODIA OPERATIONS (FR) | 2012-05-10 | — | — | US | disclosed |
| US-8071674-B2 | Compositions having HASE rheology modifiers | RHODIA OPERATIONS (FR) | 2011-12-06 | — | — | US | disclosed |
| US-20100273683-A1 | Compositions having hase rheology modifiers | SPECIALTY OPERATIONS FRANCE (FR) | 2010-10-28 | — | — | US | disclosed |
| US-7772421-B2 | Compositions having HASE rheology modifiers | RHODIA INC. (US) | 2010-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273683-A1 | Compositions having hase rheology modifiers | WEE2, CCNE2, HPSE | TSHR 4655/4885THRB 4602/4885PLA2G2C 442/4885 |
| US-20120123149-A1 | Composition having hase rheology modifiers | WEE2, CCNE2, WEE1 | TSHR 4688/4885THRB 4595/4885PLA2G2C 296/4885 |
| US-20120121523-A1 | Compositions having hase rheology modifiers | WEE2, CCNE2, HPSE | TSHR 4655/4885THRB 4602/4885PLA2G2C 442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.