Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | UGCG | Q16739 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3987347 | 0.92 | F10 (0.47) | F10MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8225135 | 0.87 | F10 (0.55) | F10MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL13069754 | 0.86 | F10 (0.42) | F10MAPK1ALDH1A1NR1I2UGCG | |
| SCHEMBL8231433 | 0.86 | F10 (0.48) | F10MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8232904 | 0.83 | F10 (0.41) | F10MAPT | |
| SCHEMBL8229933 | 0.82 | CCR4 (0.35) | F10MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8231182 | 0.79 | F10 (0.43) | F10MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL3984298 | 0.79 | F10 (0.63) | F10MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL3382279 | 0.77 | F10 (0.49) | F10KMT2ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL3382382 | 0.77 | F10 (0.55) | F10MEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007137790-A1 | ISOINDOLIN-1-ONE-, ISOINDOLIN-3-ONE- AND ISOINDOLIN-1,3-DIONE-DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-12-06 | — | — | WO | disclosed |